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Ian R Mackay
Researcher at Monash University, Clayton campus
Publications - 9
Citations - 1938
Ian R Mackay is an academic researcher from Monash University, Clayton campus. The author has contributed to research in topics: Diabetes mellitus & Latent autoimmune diabetes of adults. The author has an hindex of 9, co-authored 9 publications receiving 1858 citations. Previous affiliations of Ian R Mackay include Monash University.
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UKPDS 25: autoantibodies to islet-cell cytoplasm and glutamic acid decarboxylase for prediction of insulin requirement in type 2 diabetes
Robert C. Turner,Irene M Stratton,V A Horton,Sue Manley,Paul Zimmet,Ian R Mackay,M Shattock,Gian Franco Bottazzo,Rury R. Holman +8 more
TL;DR: In this article, the presence of either or both antibodies characterises a subtype of diabetes and provides better prediction of requirement for insulin therapy by 6 years' follow-up than clinical variables.
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Antibodies to Glutamic Acid Decarboxylase Reveal Latent Autoimmune Diabetes Mellitus in Adults With a Non—Insulin-Dependent Onset of Disease
TL;DR: In a proportion of adults who present with NIDDM, a slowly evolving autoimmune insulitis can be revealed by testing for anti-GAD, which could have important connotations not only for early intervention, but also for the correct classification of diabetes.
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Latent Autoimmune Diabetes Mellitus in Adults (LADA): the Role of Antibodies to Glutamic Acid Decarboxylase in Diagnosis and Prediction of Insulin Dependency
Paul Zimmet,Tiinamaija Tuomi,Ian R Mackay,Merrill J. Rowley,William J. Knowles,Cohen M,Lang Da +6 more
TL;DR: Testing for anti‐GAD in adult‐onset non‐obese diabetic patients should be a routine procedure in order to detect latent insulin‐dependency at the earliest possible stage, since this assay can assist in the correct classification of diabetes, and more appropriate therapy.
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The low prevalence of immunogenetic markers in Korean adult-onset IDDM patients.
Yongsoo Park,Hong Kyu Lee,Chang Soon Koh,Hun-Ki Min,Merrill J. Rowley,Ian R Mackay,Paul Zimmet,Bridget J. McCarthy,Erin Mccanlies,J. S. Dorman,Massimo Trucco +10 more
TL;DR: The low prevalence of anti-GAD antibodies and HLA-DQA1 and DQB1 susceptibility alleles among recent-onset NIDDM patients, which was similar to observations in control subjects, suggests that diabetes in Korean adults is unlikely to have an autoimmune component to its pathogenesis.
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Antibodies to pancreatic islet cell antigens in diabetes seen in Southern India with particular reference to fibrocalculous pancreatic diabetes.
TL;DR: The data suggest that in FCPD, the frequency of auto‐antibodies is low and its aetiology is probably not linked to autoimmunity in the majority of the patients.