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Ifechukwude Joachim Biose
Researcher at Tulane University
Publications - 20
Citations - 116
Ifechukwude Joachim Biose is an academic researcher from Tulane University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 4, co-authored 9 publications receiving 46 citations. Previous affiliations of Ifechukwude Joachim Biose include University of Glasgow & Cross River University of Technology.
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Journal ArticleDOI
In Vivo protection from SARS-CoV-2 infection by ATN-161 in k18-hACE2 transgenic mice.
Narayanappa Amruta,Elizabeth B. Engler-Chiurazzi,Isabel C. Murray-Brown,Timothy E. Gressett,Ifechukwude Joachim Biose,Wesley H. Chastain,Jaime B. Befeler,Gregory J. Bix +7 more
TL;DR: In this paper, the authors further evaluated the therapeutic potential of ATN-161 on SARS-CoV-2 infection in k18-hACE2 transgenic mice in vivo.
Journal ArticleDOI
Perlecan, A Multi-Functional, Cell-Instructive, Matrix-Stabilizing Proteoglycan With Roles in Tissue Development Has Relevance to Connective Tissue Repair and Regeneration
Anthony James Hayes,Brooke L. Farrugia,Ifechukwude Joachim Biose,Gregory J. Bix,James Melrose +4 more
TL;DR: This review highlights the multifunctional properties of perlecan (HSPG2) and its potential roles in repair biology and suggests that a greater understanding of the functional working of the neuromuscular junction may be insightful in therapeutic approaches in the treatment of neuromUScular disorders.
Journal ArticleDOI
Perlecan Domain-V Enhances Neurogenic Brain Repair After Stroke in Mice
Amanda L Trout,Michael P. Kahle,Michael P. Kahle,Jill Roberts,Aileen Marcelo,Leon de Hoog,Jeffery A. Boychuk,Stephen Grupke,Antonio Berretta,Emma K. Gowing,Carie R. Boychuk,Amanda A. Gorman,Danielle N. Edwards,Ibolya Rutkai,Ifechukwude Joachim Biose,Hatsue Ishibashi-Ueda,Masafumi Ihara,Bret N. Smith,Andrew N. Clarkson,Gregory J. Bix +19 more
TL;DR: It is demonstrated that domain V is chronically increased in the brains of human stroke patients, suggesting that it is present during post-stroke neurogenic periods and that delayed DV administration after experimental stroke enhances neurogenesis and improves recovery in an α2β1 integrin-mediated fashion.
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Impact of stroke co-morbidities on cortical collateral flow following ischaemic stroke.
Ifechukwude Joachim Biose,Ifechukwude Joachim Biose,Deborah Dewar,I. Mhairi Macrae,Christopher McCabe +4 more
TL;DR: Hyperglycaemia at the time of arterial occlusion or pre-existing hypertension impaired the dynamic recruitment of cortical collaterals after pMCAO, and the impairment of collateral recruitment may contribute to the detrimental effects these comorbidities have on stroke outcome.
Journal ArticleDOI
Chronic nicotine administration does not alter cognitive or mood associated behavioural parameters
Omamuyovwi M. Ijomone,Omamuyovwi M. Ijomone,Olayemi K. Olaibi,Christian,Ifechukwude Joachim Biose,Samuel Anthony Tete,Polycarp U. Nwoha +6 more
TL;DR: The study shows that nicotine does not produce long-term changes in some cognitive and mood associated behaviours, thus suggesting it could be well tolerated even following chronic administration.