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Ignacio Ochoa
Researcher at University of Zaragoza
Publications - 64
Citations - 1600
Ignacio Ochoa is an academic researcher from University of Zaragoza. The author has contributed to research in topics: Self-healing hydrogels & Medicine. The author has an hindex of 20, co-authored 55 publications receiving 1281 citations. Previous affiliations of Ignacio Ochoa include Carlos III Health Institute & International Association of Classification Societies.
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Journal ArticleDOI
The pro-angiogenic properties of multi-functional bioactive glass composite scaffolds.
LC Lutz-Christian Gerhardt,Kate L. Widdows,M. Erol,Charles W. Burch,J.A. Sanz-Herrera,Ignacio Ochoa,Rolf Stämpfli,Iman S. Roqan,Simon M. Gabe,Tahera Ansari,Aldo R. Boccaccini,Aldo R. Boccaccini +11 more
TL;DR: P porous 3D composite scaffolds, optimised with respect to the BG filler content capable of inducing angiogenic response, show potential for the regeneration of hard-soft tissue defects and increased bone formation arising from enhanced vascularisation of the construct.
Journal ArticleDOI
Permeability evaluation of 45S5 Bioglass-based scaffolds for bone tissue engineering.
Ignacio Ochoa,J.A. Sanz-Herrera,José Manuel García-Aznar,Manuel Doblaré,D.M. Yunos,Aldo R. Boccaccini +5 more
TL;DR: Darcy's experiments were carried out in order to determine the relationship between the pressure drop gradient and the fluid flow velocity in Bioglass-based scaffolds to obtain the scaffold's permeability.
Journal ArticleDOI
Development and characterization of a microfluidic model of the tumour microenvironment.
Jose M. Ayuso,Jose M. Ayuso,María Virumbrales-Muñoz,María Virumbrales-Muñoz,Alodia Lacueva,Alodia Lacueva,Pilar M. Lanuza,Pilar M. Lanuza,Elisa Checa-Chavarria,Pablo Botella,Eduardo Fernández,Manuel Doblaré,Manuel Doblaré,Simon J. Allison,Roger M. Phillips,Julián Pardo,Luis J. Fernández,Luis J. Fernández,Ignacio Ochoa,Ignacio Ochoa +19 more
TL;DR: The versatility of this microfluidic platform allows for different aspects of the microenvironment to be monitored and dissected and the device’s potential to enable more physiological in vitro drug screening is indicated.
Journal ArticleDOI
An experimental study of the mouse skin behaviour: damage and inelastic aspects.
María Jesús Muñoz,J.A. Bea,Jose F. Rodriguez,Ignacio Ochoa,J. Grasa,A. Pérez del Palomar,Pilar Zaragoza,Rosario Osta,Manuel Doblaré +8 more
TL;DR: Good correlation was observed between the residual strain and the maximum strain previously attained by the sample during loading for all samples, however, the correlation was different between genders.
Journal ArticleDOI
Glioblastoma on a microfluidic chip: Generating pseudopalisades and enhancing aggressiveness through blood vessel obstruction events.
Jose M. Ayuso,Rosa Monge,Rosa Monge,Alicia Martínez-González,María Virumbrales-Muñoz,María Virumbrales-Muñoz,Guillermo A. Llamazares,Guillermo A. Llamazares,Javier Berganzo,Aurelio Hernández-Laín,Jorge Santolaria,Manuel Doblaré,Manuel Doblaré,Christopher G. Hubert,Jeremy N. Rich,Pilar Sánchez-Gómez,Víctor M. Pérez-García,Ignacio Ochoa,Ignacio Ochoa,Luis J. Fernández,Luis J. Fernández +20 more
TL;DR: A new microfluidic model of GBM is presented that mimics the dynamics of pseudopalisade formation and shows the potential of microfluidity devices as advanced artificial systems capable of modeling in vivo nutrient and oxygen gradients during tumor evolution.