Pilar Zaragoza

TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.

TL;DR: The progression of the disease is discussed from the viewpoint of the potential biomarkers described to date in human and animal model samples and potential therapeutic strategies for ALS treatment and future, innovative perspectives are considered.

TL;DR: A cattle genetic linkage map was constructed which covers more than 95 percent of the bovine genome at medium density as mentioned in this paper, and the resultant genome-wide comparative analyses indicate that while there is a greater conservation of synteny between cattle and humans compared with mice, the conservation of gene order between cows and humans is much less than would be expected from the conserving synteny.

TL;DR: It was concluded that under normal Spanish commercial conditions, pigs subjected to short transport showed a more intense stress response and poorer meat quality than animals subjected to moderately long transport when they were immediately slaughtered on arrival at the slaughterhouse.

TL;DR: It is concluded that miR-206 is elevated in the circulation of symptomatic SOD1-G93A mice and possibly in human ALS patients, and is a promising candidate biomarker for this motor neuron disease.