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Ilaria Sestini
Researcher at University of Florence
Publications - 15
Citations - 903
Ilaria Sestini is an academic researcher from University of Florence. The author has contributed to research in topics: Population & Myocardial infarction. The author has an hindex of 12, co-authored 13 publications receiving 876 citations.
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Cytochrome P450 2C19 loss-of-function polymorphism, but not CYP3A4 IVS10 + 12G/A and P2Y12 T744C polymorphisms, is associated with response variability to dual antiplatelet treatment in high-risk vascular patients.
Betti Giusti,Anna Maria Gori,Rossella Marcucci,Claudia Saracini,Ilaria Sestini,Rita Paniccia,Serafina Valente,D. Antoniucci,Rosanna Abbate,Gian Franco Gensini +9 more
TL;DR: This study demonstrates, for the first time, that the *2 CYP2C19 allele is associated with higher platelet aggregability and RPR in high-risk vascular patients on dual antiplatelet treatment.
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Relation of Cytochrome P450 2C19 Loss-of-Function Polymorphism to Occurrence of Drug-Eluting Coronary Stent Thrombosis
Betti Giusti,Anna Maria Gori,Rossella Marcucci,Claudia Saracini,Ilaria Sestini,Rita Paniccia,Piergiovanni Buonamici,David Antoniucci,Rosanna Abbate,Gian Franco Gensini +9 more
TL;DR: In this paper, the role of the CYP2C19*2 polymorphism in the occurrence of stent thrombosis or the composite end point of ST and cardiac mortality within a 6-month follow-up in patients undergoing percutaneous coronary interventions with drug-eluting stent implantation on dual-antiplatelet treatment enrolled in the RECLOSE trial.
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High levels of homocysteine, lipoprotein (a) and plasminogen activator inhibitor-1 are present in patients with abdominal aortic aneurysm.
Francesco Sofi,Rossella Marcucci,Betti Giusti,Giovanni Pratesi,B. Lari,Ilaria Sestini,Patrizia Lo Sapio,Raffaele Pulli,Carlo Pratesi,Rosanna Abbate,Gian Franco Gensini +10 more
TL;DR: A significant association between abnormal levels of some metabolic parameters related to thrombosis such as Hcy, Lp(a) and PAI-1 and AAA has been observed.
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Genetic analysis of 56 polymorphisms in 17 genes involved in methionine metabolism in patients with abdominal aortic aneurysm
Betti Giusti,Claudia Saracini,Paola Bolli,Alberto Magi,Ilaria Sestini,Elena Sticchi,Giovanni Pratesi,Raffaele Pulli,Carlo Pratesi,Rosanna Abbate +9 more
TL;DR: After haplotype reconstruction, logistic regression analyses adjusted for traditional risk factors and COPD showed a significant association among AAA and AHCY, FOLH 1, MTHFD1, MTR, NNMT, PON1 and TYMS haplotypes, offering new insights into the pathogenesis of AAA.
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Low protein Z plasma levels are independently associated with acute coronary syndromes.
Sandra Fedi,Francesco Sofi,Daria Brogi,Irene Tellini,Francesca Cesari,Ilaria Sestini,Alessandra Gazzini,Marco Comeglio,Rosanna Abbate,Gian Franco Gensini +9 more
TL;DR: The results suggest a possible role of PZ in the occurrence of arterial thrombosis in patients with acute coronary syndromes.