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Indira Hewlett
Researcher at Center for Biologics Evaluation and Research
Publications - 188
Citations - 5121
Indira Hewlett is an academic researcher from Center for Biologics Evaluation and Research. The author has contributed to research in topics: Virus & Viral replication. The author has an hindex of 35, co-authored 186 publications receiving 4702 citations. Previous affiliations of Indira Hewlett include Food and Drug Administration & Silver Spring Networks.
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Journal ArticleDOI
Committee report. Nucleic acid amplification testing of blood donors for transfusion-transmitted infectious diseases: Report of the Interorganizational Task Force on Nucleic Acid Amplification Testing of Blood Donors.
Journal ArticleDOI
Current Approaches for Diagnosis of Influenza Virus Infections in Humans.
TL;DR: Diagnostic approaches currently available for detection of influenza viruses in humans, including viral isolation in cell culture, immunofluorescence assays, nucleic acid amplification tests, immunochromatography-based rapid diagnostic tests, etc are discussed.
Journal ArticleDOI
Prevention of HIV infection by passive immunization with HIV immunoglobulin.
Alfred M. Prince,Henk Reesink,Donna Pascual,Bernard Horowitz,Indira Hewlett,Krishna K. Murthy,K E Cobb,Jorg W. Eichberg +7 more
TL;DR: It is shown that HIVIG protected against a challenge dose tenfold lower than that used previously, implying that HIV vaccines should induce neutralizing antibody and may not need to induce cell-mediated immunity to be protective against exposure to HIV.
Journal ArticleDOI
Implementation of donor screening for infectious agents transmitted by blood by nucleic acid technology: update to 2003
Joliette Coste,H. W. Reesink,C. P. Engelfriet,Syria Laperche,Stuart M. Brown,Michael P. Busch,H. T. M. Cuijpers,R. Elgin,Bengt Ekermo,Jay S. Epstein,O. Flesland,Hans Erik Heier,G. Henn,J. M. Hernandez,Indira Hewlett,Catherine A. Hyland,Anthony J. Keller,Tom Krusius,S. Levičnik‐Stezina,G. Levy,C. K. Lin,Angelo R. Margaritis,L. Muylle,C. Neiderhauser,S. Pastila,Josiane Pillonel,J. Pineau,C. L. Van Der Poel,C. Politis,W.K. Roth,Silvia Sauleda,Clive R. Seed,D. Sondag‐Thull,Susan L. Stramer,M. Strong,Eleftherios C. Vamvakas,Claudio Velati,Miguel A. Vesga,A. Zanetti +38 more
TL;DR: J.J. Brown, M. P. Busch, H. Cuijpers, R. Elgin, B. E. Heier, G. Henn, J. Hewlett, C. Hyland, A. Levy, K. Roth, S. Sauleda,C.
Journal Article
HIV-1-Tat modulates the function of monocytes and alters their interactions with microvessel endothelial cells. A mechanism of HIV pathogenesis.
Robert M. Lafrenie,Larry M. Wahl,Jay S. Epstein,Indira Hewlett,Kenneth M. Yamada,Subhash Dhawan +5 more
TL;DR: The studies demonstrate that many of the effects of HIV infection on monocyte homotypic and heterotypic adhesion, protease secretion, and disruption of the endothelium can be mimicked by treatment with HIV-Tat protein alone, and suggest a mechanism where monocytes could be inappropriately activated by HIV- Tat, causing them to extravasate into underlying tissues and ultimately contribute to tissue damage as seen during the progression of AIDS.