Ines Desanlis

TL;DR: Focusing primarily on the aggrecanases and proteoglycanases, a perspective on the evolution of the ADAMTS family, their links with developmental and disease mechanisms, and key questions for the future are provided.

TL;DR: It is shown that components of the transcriptional elongation regulatory machinery, CDK9 and CYCLINT1 of the P-TEFb complex, are required to regulate neural crest specification and that expression of the proto-oncogene c- myc and c-Myc responsive genes are affected.

TL;DR: Gene identification and a phylogenetic study revealed strong conservation of the ADAMTS family and contributed to a better annotation of the Xenopus genomes.

TL;DR: In this article , the authors analyzed the contribution of the DOCK1-interacting ELMO scaffold proteins to myoblast fusion and showed that the dystrophic features of the Dysferlin -null mice, a model of limb-girdle muscular dystrophy type 2B, were reversed when expressing ELMO2 in an open conformation.

TL;DR: In this paper , an unexpected role for Angiopoietin-like 2 (ANGPTL2), a pro-inflammatory protein secreted by senescent cells, in valvulogenesis was identified.