Ioannis Sainis

TL;DR: The remarkable presence of lactic acid bacteria in the phyllosphere under the harsh conditions of the Mediterranean summer, the profound dissimilarity in the structure of bacterial communities inphyllosphere and air, and the remarkable differences of leaf microbial communities on neighbouring plants subjected to similar microbial inocula point to the importance of the leaf glandular trichome in determining colonization patterns.

TL;DR: This article revisits cyanobacterial cyclopeptides as potential novel targets for anticancer drugs by summarizing existing biomedical evidence, presenting structure-activity data and discussing developmental perspectives.

TL;DR: Considering the antitumor activity and response duration, the negligible toxicity of the highest dose investigated and the lack of drug accumulation over time, it is suggested that 50 mg given three times a week is the optimal dose for metronomic oral vinorelbine.

TL;DR: This is the first report of the presence of the hepatotoxic microcystins in the Mediterranean Sea, the first study on the accumulation of these toxins in mussels from a Mediterranean marine ecosystem and one of the few published works suggesting a potential association of microcyStins with Synechococcus and/or SyneChocystis cyanobacteria.

TL;DR: The binding affinity of 1–3 towards the intracellular molecules calf-thymus DNA and lipoxygenase were studied to determine the ability of complexes 1-3 to modify the activity of cells.