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Iris Müller
Researcher at University of Tübingen
Publications - 38
Citations - 3398
Iris Müller is an academic researcher from University of Tübingen. The author has contributed to research in topics: Platelet & Macrophage migration inhibitory factor. The author has an hindex of 22, co-authored 35 publications receiving 3162 citations. Previous affiliations of Iris Müller include Technische Universität München.
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Journal ArticleDOI
A Critical Role of Platelet Adhesion in the Initiation of Atherosclerotic Lesion Formation
Steffen Massberg,Korbinian Brand,Sabine Grüner,Sharon Page,Elke Müller,Iris Müller,Wolfgang Bergmeier,Thomas Richter,Michael Lorenz,Ildiko Konrad,Bernhard Nieswandt,Meinrad Gawaz +11 more
TL;DR: It is shown in vivo that platelets adhere to the vascular endothelium of the carotid artery in ApoE − / − mice before the development of manifest atherosclerotic lesions, establishing the platelet as a major player in initiation of the atherogenetic process.
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Prevalence of clopidogrel non-responders among patients with stable angina pectoris scheduled for elective coronary stent placement.
TL;DR: A subgroup of patients undergoing PCI does not adequately respond to clopidogrel, which may correspond to the occurrence of thromboischemic complications and point-of-care testing may help to identify these patients who may then benefit from an alternative antiplatelet therapy.
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Effect of a high loading dose of clopidogrel on platelet function in patients undergoing coronary stent placement.
Iris Müller,Melchior Seyfarth,Silja Rüdiger,Beate Wolf,Gisela Pogatsa-Murray,Albert Schömig,Meinrad Gawaz +6 more
TL;DR: The present study sought to investigate the antiplatelet effect of various doses of clopidogrel in patients undergoing coronary stent placement; comparison was made with standard ticlopidine treatment.
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Soluble glycoprotein VI dimer inhibits platelet adhesion and aggregation to the injured vessel wall in vivo
Steffen Massberg,Ildiko Konrad,Andreas Bültmann,Christian Schulz,Götz Münch,Mario Peluso,Michael Lorenz,Simon Schneider,Felicitas Besta,Iris Müller,Bin Hu,Harald Langer,Elisabeth Kremmer,Martina Rudelius,Ulrich Heinzmann,Martin Ungerer,Meinrad Gawaz +16 more
TL;DR: Findings further substantiate the critical role of the collagen receptor GPVI in the initiation of thrombus formation at sites of vascular injury and identify soluble GPVI as a promising antithrombotic strategy.
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Expression of stromal-cell-derived factor-1 on circulating platelets is increased in patients with acute coronary syndrome and correlates with the number of CD34+ progenitor cells
Konstantinos Stellos,Boris Bigalke,Harald F. Langer,Tobias Geisler,Annika Schad,Andreas Kögel,Florian Pfaff,Dimitrios Stakos,Peter Seizer,Iris Müller,Patrick Htun,Stephan Lindemann,Meinrad Gawaz +12 more
TL;DR: Platelet-bound SDF-1 may play an important role in peripheral homing of circulating progenitor cells thus in tissue regeneration in patients with acute coronary syndrome independent of cardiovascular risk factors and medication.