I
Irma Sosa-González
Publications - 4
Citations - 86
Irma Sosa-González is an academic researcher. The author has contributed to research in topics: Chorioamnionitis & Amnion. The author has an hindex of 4, co-authored 4 publications receiving 71 citations.
Papers
More filters
Journal ArticleDOI
Progesterone Elicits an Inhibitory Effect upon LPS-Induced Innate Immune Response in Pre-Labor Human Amniotic Epithelium
Pilar Flores-Espinosa,Montzerrat Pineda-Torres,Rodrigo Vega-Sanchez,Guadalupe Estrada-Gutierrez,Aurora Espejel-Nuñez,Arturo Flores-Pliego,Rolando Maida-Claros,Yuriria Paredes-Vivas,Iyari Morales-Méndez,Irma Sosa-González,Angel Chávez-Mendoza,Veronica Zaga-Clavellina +11 more
TL;DR: Infection of human fetal membranes elicits secretion of pro‐inflammatory modulators through its innate immune capacities and the effect of lipopolysacharide and progesterone upon expression of TLR‐4/MyD88, TNFα,IL‐6, IL‐8, IL-10, and HBD2 on the human amniotic epithelium is investigated.
Journal ArticleDOI
Tissue-specific human beta-defensins (HBD)-1, HBD-2 and HBD-3 secretion profile from human amniochorionic membranes stimulated with Candida albicans in a two-compartment tissue culture system
Veronica Zaga-Clavellina,Martha Ruiz,Pilar Flores-Espinosa,Rodrigo Vega-Sanchez,Arturo Flores-Pliego,Guadalupe Estrada-Gutierrez,Irma Sosa-González,Iyari Morales-Méndez,Mauricio Osorio-Caballero +8 more
TL;DR: The aim of this work was to characterize the individual contribution of the amnion (AMN) and choriodecidua (CHD) regions to the secretion of H BD-1, HBD-2 and HBD3, after stimulation with Candida albicans, mainly in the CHD, which is the first region to become infected during an ascending infection.
Journal ArticleDOI
Tissue-specific IL-10 secretion profile from term human fetal membranes stimulated with pathogenic microorganisms associated with preterm labor in a two-compartment tissue culture system.
Veronica Zaga-Clavellina,Pilar Flores-Espinosa,Montzerrat Pineda-Torres,Irma Sosa-González,Rodrigo Vega-Sanchez,Guadalupe Estrada-Gutierrez,Aurora Espejel-Nuñez,Arturo Flores-Pliego,Rolando Maida-Claros,Higinio Estrada-Juárez,Angel Chávez-Mendoza +10 more
TL;DR: Synthesis and secretion of IL-10 in response to three different pathogens associated with intrauterine infection and preterm birth are differential and depend on the nature of the microorganism and initial contact region.
Journal ArticleDOI
Escherichia coli-induced temporal and differential secretion of heat-shock protein 70 and interleukin-1β by human fetal membranes in a two-compartment culture system.
Mauricio Osorio-Caballero,C. Perdigón-Palacio,Guadalupe García-López,Oscar Flores-Herrera,Sofia Olvera-Sanchez,Iyari Morales-Méndez,Irma Sosa-González,Jesus F. Acevedo,Alberto Martín Guzmán-Grenfell,Anayansi Molina-Hernández,Néstor F. Díaz,Héctor Flores-Herrera +11 more
TL;DR: Human fetal membranes responded actively to E. coli infection, with an increase in Hsp-70 during the first hours of infection, and after 24 h of incubation, HSp-70 was downregulated and the liberation of IL-1β was observed, indicating that E.coli induces pro-inflammatory cytokines and degradative metalloproteinases in fetal membranes.