R
Rodrigo Vega-Sanchez
Publications - 25
Citations - 555
Rodrigo Vega-Sanchez is an academic researcher. The author has contributed to research in topics: Chemokine & Tumor necrosis factor alpha. The author has an hindex of 12, co-authored 20 publications receiving 439 citations.
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Journal ArticleDOI
Evidence for a Role for the Adaptive Immune Response in Human Term Parturition
Nardhy Gomez-Lopez,Rodrigo Vega-Sanchez,Marisol Castillo-Castrejon,Roberto Romero,Karen Cubeiro-Arreola,Felipe Vadillo-Ortega +5 more
TL;DR: The purpose of this study was to characterize the immunophenotype of choriodecidual leukocytes as well as the expression of inflammatory mediators in human spontaneous parturition at term.
Journal ArticleDOI
Fetal membranes exhibit selective leukocyte chemotaxic activity during human labor.
Nardhy Gomez-Lopez,Guadalupe Estrada-Gutierrez,Jiménez-Zamudio L,Rodrigo Vega-Sanchez,Felipe Vadillo-Ortega +4 more
TL;DR: It is concluded that fetal membrane extracts obtained from women during labor exhibit selective chemotaxis for specific leukocyte subpopulations in vitro, which may contribute to a microenvironment composed of specificLeukocytes that promotes and amplifies biochemical changes in the fetal membranes during labor.
Journal ArticleDOI
Innate Immune Cells and Toll-like Receptor-Dependent Responses at the Maternal-Fetal Interface.
Andrea Olmos-Ortiz,Pilar Flores-Espinosa,Ismael Mancilla-Herrera,Rodrigo Vega-Sanchez,Lorenza Díaz,Veronica Zaga-Clavellina +5 more
TL;DR: Some of the various roles that the innate immune system plays at the maternal–fetal interface are outlined, in terms of their specific cytokine/chemokine/antimicrobial peptide expression profiles throughout pregnancy.
Journal ArticleDOI
Placental blood leukocytes are functional and phenotypically different than peripheral leukocytes during human labor.
Rodrigo Vega-Sanchez,Nardhy Gomez-Lopez,Arturo Flores-Pliego,Susana Clemente-Galvan,Guadalupe Estrada-Gutierrez,Alejandro Zentella-Dehesa,Rolando Maida-Claros,Jorge Beltrán-Montoya,Felipe Vadillo-Ortega +8 more
TL;DR: The results support the existence of selective subsets of leukocytes recruited to the maternal-fetal interface that may participate in the triggering of parturition.
Journal ArticleDOI
Progesterone Elicits an Inhibitory Effect upon LPS-Induced Innate Immune Response in Pre-Labor Human Amniotic Epithelium
Pilar Flores-Espinosa,Montzerrat Pineda-Torres,Rodrigo Vega-Sanchez,Guadalupe Estrada-Gutierrez,Aurora Espejel-Nuñez,Arturo Flores-Pliego,Rolando Maida-Claros,Yuriria Paredes-Vivas,Iyari Morales-Méndez,Irma Sosa-González,Angel Chávez-Mendoza,Veronica Zaga-Clavellina +11 more
TL;DR: Infection of human fetal membranes elicits secretion of pro‐inflammatory modulators through its innate immune capacities and the effect of lipopolysacharide and progesterone upon expression of TLR‐4/MyD88, TNFα,IL‐6, IL‐8, IL-10, and HBD2 on the human amniotic epithelium is investigated.