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Isamu Okamoto
Researcher at Kyushu University
Publications - 458
Citations - 25482
Isamu Okamoto is an academic researcher from Kyushu University. The author has contributed to research in topics: Lung cancer & Epidermal growth factor receptor. The author has an hindex of 64, co-authored 413 publications receiving 19982 citations. Previous affiliations of Isamu Okamoto include Emory University & Kumamoto University.
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Journal ArticleDOI
Amrubicin for non-small-cell lung cancer and small-cell lung cancer.
TL;DR: Results are promising for the treatment of both NSCLC and SCLC, and further clinical trials will clarify the status of amrubicin in the Treatment of lung cancer.
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Phase II Study of Combination Therapy with S-1 and Irinotecan for Advanced Non–Small Cell Lung Cancer: West Japan Thoracic Oncology Group 3505
Isamu Okamoto,Takashi Nishimura,Masaki Miyazaki,Hiroshige Yoshioka,Akihito Kubo,Koji Takeda,Noriyuki Ebi,Shunichi Sugawara,Nobuyuki Katakami,Masahiro Fukuoka,Kazuhiko Nakagawa +10 more
TL;DR: The combination of S-1 and irinotecan is a potential alternative option with a favorable toxicity profile for the treatment of advanced NSCLC and warrants further evaluation in randomized trials.
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Clinical Significance of PD-L1 Expression in Brain Metastases from Non-small Cell Lung Cancer
Shinkichi Takamori,Gouji Toyokawa,Isamu Okamoto,Kazuki Takada,Fumihiko Kinoshita,Yuka Kozuma,Taichi Matsubara,Naoki Haratake,Takaki Akamine,Nobutaka Mukae,Fumihiko Hirai,Tetsuzo Tagawa,Yoshinao Oda,Toru Iwaki,Koji Iihara,Yoichi Nakanishi,Yoshihiko Maehara +16 more
TL;DR: The PD-L1 expression in BM from NSCLC may be associated with local recurrence following surgery, and the smoking- or radiotherapy-derived effects.
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Clinical utility of pretreatment Glasgow prognostic score in non-small-cell lung cancer patients treated with immune checkpoint inhibitors.
Shinkichi Takamori,Kazuki Takada,Mototsugu Shimokawa,Taichi Matsubara,Takatoshi Fujishita,Kensaku Ito,Ryo Toyozawa,Masafumi Yamaguchi,Tatsuro Okamoto,Yasuto Yoneshima,Kentaro Tanaka,Isamu Okamoto,Tetsuzo Tagawa,Masaki Mori +13 more
TL;DR: It is reported for the first time that GPS represents a simple and useful prognostic factor in NSCLC patients treated with ICIs and should be validated prospectively.
Journal ArticleDOI
The CLIP1-LTK fusion is an oncogenic driver in non-small-cell lung cancer.
Hiroki Izumi,Shingo Matsumoto,Jie Liu,Kosuke Tanaka,Shunta Mori,Kumiko Hayashi,Shogo Kumagai,Yuji Shibata,Takuma Hayashida,Kana Watanabe,Tatsuro Fukuhara,Takaya Ikeda,Kiyotaka Yoh,Terufumi Kato,Kazumi Nishino,Atsushi Nakamura,Ichiro Nakachi,Shoichi Kuyama,Naoki Furuya,Jun Sakakibara-Konishi,Isamu Okamoto,Kageaki Taima,Noriyuki Ebi,Haruko Daga,Akira Yamasaki,Masahiro Kodani,Hibiki Udagawa,Keisuke Kirita,Yoshitaka Zenke,Kaname Nosaki,Eri Sugiyama,Tetsuya Sakai,Tokiko Nakai,Genichiro Ishii,Seiji Niho,Atsushi Ohtsu,Susumu Kobayashi,Susumu Kobayashi,Koichi Goto +38 more
TL;DR: In this article, the authors identify a novel fusion transcript of CLIP1 and LTK using whole-transcriptome sequencing in a multi-institutional genome screening platform (LC-SCRUM-Asia, UMIN000036871).