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Isao Kubota
Researcher at Yamagata University
Publications - 457
Citations - 10043
Isao Kubota is an academic researcher from Yamagata University. The author has contributed to research in topics: Heart failure & Population. The author has an hindex of 46, co-authored 457 publications receiving 9120 citations. Previous affiliations of Isao Kubota include University Hospitals of Cleveland & Fukushima Medical University.
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Prevalence of atrial fibrillation in the general population of Japan: an analysis based on periodic health examination.
Hiroshi Inoue,Akira Fujiki,Hideki Origasa,Satoshi Ogawa,Ken Okumura,Isao Kubota,Yoshifusa Aizawa,Takeshi Yamashita,Hirotsugu Atarashi,Minoru Horie,Tohru Ohe,Yoshinori Doi,Akihiko Shimizu,Akiko Chishaki,Tetsunori Saikawa,Katsusuke Yano,Akira Kitabatake,Hideo Mitamura,Itsuo Kodama,Shiro Kamakura +19 more
TL;DR: The prevalence of AF increased in Japan as the population aged, as in Western countries, and the overall prevalence in Japan is approximately two-thirds of that in the USA.
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Toll-Like Receptor-2 Modulates Ventricular Remodeling After Myocardial Infarction
Tetsuro Shishido,Naoki Nozaki,Seiji Yamaguchi,Yoko Shibata,Joji Nitobe,Takuya Miyamoto,Hiroki Takahashi,Takanori Arimoto,Kunihiko Maeda,Mitsunori Yamakawa,Osamu Takeuchi,Shizuo Akira,Yasuchika Takeishi,Isao Kubota +13 more
TL;DR: Data suggest that TLR-2 plays an important role in ventricular remodeling after myocardial infarction and indicates that Toll-like receptors are activated by endogenous signals, such as heat shock proteins and oxidative stress.
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The prognostic importance of objective nutritional indexes in patients with chronic heart failure
Taro Narumi,Takanori Arimoto,Akira Funayama,Shinpei Kadowaki,Yoichiro Otaki,Satoshi Nishiyama,Hiroki Takahashi,Tetsuro Shishido,Takehiko Miyashita,Takuya Miyamoto,Tetsu Watanabe,Isao Kubota +11 more
TL;DR: Evaluation of nutritional status may provide additional prognostic information in patients with CHF and showed that there was a significantly higher incidence of cardiovascular events in patients who were malnourished than in those who were not.
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Modulation of doxorubicin-induced cardiac dysfunction in toll-like receptor-2-knockout mice.
TL;DR: Findings suggest that TLR-2 may play a role in the regulation of inflammatory and apoptotic mediators in the heart after Dox administration.
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Pentraxin 3, a new marker for vascular inflammation, predicts adverse clinical outcomes in patients with heart failure.
Satoshi Suzuki,Yasuchika Takeishi,Takeshi Niizeki,Yo Koyama,Tatsuro Kitahara,Toshiki Sasaki,Mina Sagara,Isao Kubota +7 more
TL;DR: The highest fourth quartile of plasma PTX3 levels was associated with the highest risk of cardiac events and provides important prognostic information for the risk stratification of patients with heart failure.