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Ivan Maillard
Researcher at University of Pennsylvania
Publications - 205
Citations - 12407
Ivan Maillard is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Notch signaling pathway & T cell. The author has an hindex of 52, co-authored 183 publications receiving 10429 citations. Previous affiliations of Ivan Maillard include University Hospital of Lausanne & University of Michigan.
Papers
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Journal ArticleDOI
Promising Survival for Patients With Newly Diagnosed Glioblastoma Multiforme Treated With Concomitant Radiation Plus Temozolomide Followed by Adjuvant Temozolomide
Roger Stupp,Pierre Yves Dietrich,Sandrine Ostermann Kraljevic,Alessia Pica,Ivan Maillard,Phillipe Maeder,Reto Meuli,Robert C. Janzer,Gianpaolo Pizzolato,Raymond Miralbell,F. Porchet,Luca Regli,Nicolas de Tribolet,René O. Mirimanoff,Serge Leyvraz +14 more
TL;DR: This regimen of concomitant chemoradiotherapy followed by adjuvant chemotherapy may prolong the survival of patients with glioblastoma.
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Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells
Kelli L. VanDussen,Alexis J. Carulli,Theresa M. Keeley,Sanjeevkumar R. Patel,Brent J. Puthoff,Scott T. Magness,Ivy T. Tran,Ivan Maillard,Christian W. Siebel,Åsa Kolterud,Ann S. Grosse,Deborah L. Gumucio,Stephen A. Ernst,Yu Hwai Tsai,Peter J. Dempsey,Linda C. Samuelson +15 more
TL;DR: It is shown in mice that Notch directly targets the crypt base columnar (CBC) cell to maintain stem cell activity and to regulate cell fate choice to control epithelial cell homeostasis.
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Notch Signaling in Cancer
TL;DR: This review critically review literature pertaining to the role of Notch signaling in several cancers, and discusses possible therapeutic targets in the Notch pathway.
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Regulation of lymphoid development, differentiation, and function by the notch pathway
TL;DR: The Notch pathway is gaining increasing recognition as a key regulator of developmental choices, differentiation, and function throughout the hematolymphoid system as well as current controversies and challenges in the field.
Journal ArticleDOI
Notch signaling controls the generation and differentiation of early T lineage progenitors.
Arivazhagan Sambandam,Ivan Maillard,Valerie P. Zediak,Lanwei Xu,Rachel M. Gerstein,Jon C. Aster,Warren S. Pear,Avinash Bhandoola +7 more
TL;DR: An immature subset of early T lineage progenitors in the thymus that expressed the tyrosine kinase receptor Flt3 and had preserved B lineage potential at low progenitor frequency is identified.