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Ivana Ferrero

Researcher at University of Turin

Publications -  58
Citations -  3273

Ivana Ferrero is an academic researcher from University of Turin. The author has contributed to research in topics: Mesenchymal stem cell & Transplantation. The author has an hindex of 23, co-authored 51 publications receiving 2994 citations. Previous affiliations of Ivana Ferrero include Boston Children's Hospital & University of Milan.

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Expansion of Mesenchymal Stem Cells Isolated From Pediatric and Adult Donor Bone Marrow

TL;DR: The enormous plasticity of mesenchymal stem cells (MSCs) suggests an improvement of a standard protocol of isolation and ex vivo expansion for experimental and clinical use and suggests that MSCs can be isolated and expanded from most healthy donors, providing for an autologous source of stem cells.
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Human mesenchymal stem cell transplantation extends survival, improves motor performance and decreases neuroinflammation in mouse model of amyotrophic lateral sclerosis.

TL;DR: Human bone marrow mesenchymal stem cells are a good candidate for ALS cell therapy: they can survive and migrate after transplantation in the lumbar spinal cord, where they prevent astrogliosis and microglial activation and delay ALS-related decrease in the number of motoneurons, thus resulting in amelioration of the motor performance.
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Human mesenchymal stem cells as a two-edged sword in hepatic regenerative medicine: engraftment and hepatocyte differentiation versus profibrogenic potential

TL;DR: Transplanted hMSCs have the potential to migrate into normal and injured liver parenchyma, but differentiation into hepatocyte-like cells is a rare event and pro-fibrogenic potential of hMSC transplant should be not under-evaluated.
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Stem cell treatment in Amyotrophic Lateral Sclerosis.

TL;DR: The results seem to demonstrate that MSCs represent a good chance for stem cell cell-based therapy in ALS and that intraspinal injection of M SCs is safe also in the long term.