Sebastiano Colombatto

TL;DR: The problem of the assessment of the minimum amount of Gd(III) complexes necessary for the MR imaging‐visualization of cells has been addressed by reporting the authors' observations on the cell‐internalization of GD(III), and selected examples are reported.

TL;DR: ObR activation in HSCs leads to increased expression of proinflammatory and proangiogenic cytokines, indicating a complex role for leptin in the regulation of the liver wound‐healing response.

TL;DR: It is indicated that in cancer cells, early redox mechanisms can switch on hypoxia-dependent EMT programme whereas increased invasiveness is sustained by late and HIF-1alpha-dependent release of VEGF.

TL;DR: Transplanted hMSCs have the potential to migrate into normal and injured liver parenchyma, but differentiation into hepatocyte-like cells is a rare event and pro-fibrogenic potential of hMSC transplant should be not under-evaluated.

TL;DR: This review offers a comprehensive introduction to describe major relevant features of EMT, followed by sections dedicated on those signaling mechanisms that are known to regulate or affect the process, including the recently proposed role for oxidative stress and reactive oxygen species (ROS).