J
J. A. Tsenov
Researcher at Bulgarian Academy of Sciences
Publications - 27
Citations - 471
J. A. Tsenov is an academic researcher from Bulgarian Academy of Sciences. The author has contributed to research in topics: Ab initio & Carbanion. The author has an hindex of 12, co-authored 27 publications receiving 419 citations.
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Journal ArticleDOI
Antihelminthic activity of some newly synthesized 5(6)-(un)substituted-1H-benzimidazol-2-ylthioacetylpiperazine derivatives.
Anelia Ts. Mavrova,Kamelya K. Anichina,Dimitar Vuchev,J. A. Tsenov,Pavletta Denkova,Magdalena S. Kondeva,Mitka K. Micheva +6 more
TL;DR: The antiparasitic screening showed that compounds 18-24 exhibited higher activity against Trichinella spiralis in vitro in comparison to methyl 5-(propylthio)-1H-benzimidazol-2-yl-carbamate (albendazole).
Journal ArticleDOI
Synthesis and antitrichinellosis activity of some 2-substituted-[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-ones
Anelia Ts. Mavrova,Kamelya K. Anichina,Dimitar Vuchev,J. A. Tsenov,Magdalena S. Kondeva,Mitka K. Micheva +5 more
TL;DR: The results of the hepatot toxicity test showed that the compounds 4a and 4b possess hepatotoxicity comparable to that of albendazole.
Journal ArticleDOI
IR spectra and structure of 2,5-pyrrolidinedione (succinimide) and of its nitranion: experimental and ab initio MO studies
TL;DR: The structure of succinimide has been studied on the basis of both quantitative IR spectra and ab initio RHF and MP2 calculations as discussed by the authors, and the theory describes the strong frequency decrease (down to 138 cm−1) and the twofold increase in both the intensity and splitting of the carbonyl stretching bands, caused by the conversion of the 2,5-pyrrolidinedione molecule into the nitranion.
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Synthesis and antiproliferative activity of some new thieno[2,3-d]pyrimidin-4(3H)-ones containing 1,2,4-triazole and 1,3,4-thiadiazole moiety.
TL;DR: The biological data highlighted that the nature and the position of the substituents influence both the cytotoxicity to the cancer cells and the proliferation properties to Lep3 of the tested compounds.
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Design, synthesis and antiproliferative properties of some new 5-substituted-2-iminobenzimidazole derivatives.
TL;DR: The obtained results prove the selective cytotoxicity of the tested compounds and are promising for further evaluation of the investigated compounds in vivo experiments using experimentally induced tumors in laboratory animals.