J
J. C. Wootton
Researcher at University of Leeds
Publications - 3
Citations - 502
J. C. Wootton is an academic researcher from University of Leeds. The author has contributed to research in topics: Gene & Mutant. The author has an hindex of 3, co-authored 3 publications receiving 491 citations.
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Inducible erythromycin resistance in staphlyococci is encoded by a member of the ATP‐binding transport super‐gene family
TL;DR: The deduced sequence of the 488‐amino‐acid protein (MsrA) revealed the presence of two ATP‐binding motifs homologous to those of a family of transport‐related proteins from Gram‐negative bacteria and eukaryotic cells, including the P‐glycoprotein responsible for multidrug resistance.
Journal ArticleDOI
Sequence of nifL from Klebsiella pneumoniae: mode of action and relationship to two families of regulatory proteins.
Martin Drummond,J. C. Wootton +1 more
TL;DR: The nucleotide sequence of K. pneumoniae nifL, which negatively regulates nif transcription in response to oxygen and fixed nitrogen, appears to lack a DNA‐binding motif, consistent with evidence that NifL represses by interacting directiy with NifA.
Journal ArticleDOI
Single and multiple mutations affecting properties of the regulatory gene nodD of Rhizobium.
TL;DR: Doubly mutant derivatives of nodD were constructed by making nodD genes with a mutation that conferred the ability to activate transcription of nod genes in the absence of inducers plus another that abolished autoregulation and/or flavonoid‐dependent nod gene activation.