J
J. Cristobal Lopez
Researcher at Spanish National Research Council
Publications - 168
Citations - 2439
J. Cristobal Lopez is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Radical cyclization & Glycosyl. The author has an hindex of 24, co-authored 168 publications receiving 2263 citations. Previous affiliations of J. Cristobal Lopez include North Carolina State University & Durham University.
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One-pot synthesis of 1-exo-alkylidene-2,3-anhydro furanoses: convenient precursors for exo-glycals and functionalized C-glycals.
TL;DR: 1-exo-Methylene-2,3-anhydro furanoses, obtained from C-glycals in a one-pot, three step operation can be readily transformed into functionalized C- glycals by palladium-catalyzed nucleophilic addition.
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A Stereodivergent Approach to 5a‐Carba‐α‐D‐gluco‐, ‐α‐D‐galacto and ‐β‐L‐gulopyranose Pentaacetates from D‐Mannose, Based on 6‐exo‐dig Radical Cyclization and Barton−McCombie Radical Deoxygenation
TL;DR: The carbasugars, 5a-carba-α-D-gluco-, -α -D-galacto and -β-L-gulopyranose pentaacetates 42, 35 and 28 respectively, have been prepared in a stereodivergent manner from D-mannose as discussed by the authors.
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n-Pentenyl glycosides as mediators in the asymmetric synthesis of monosubstituted chiral nonracemic tetrahydrofurans and .gamma.-lactones
TL;DR: In this paper, the authors focused on asymmetric induction in the 2-(bromomethyl) furan that is liberated, and rationalization of this observation is based on the assumption that the molecule reacts from the favored ground-state orientation, wherein the exo anomeric effect is displayed.
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Photochemically Induced Addition of 2-Propanol to Hex-2-enono-δ-lactones Followed by Radical Cyclization: A Novel Entry to Branched Cyclohexanes and Cyclopentanes from Carbohydrates
TL;DR: In this paper, photochemically induced conjugated addition of 2-propanol to carbohydrate-derived hex-2-enono-δ-lactones 7−10, substituted at C-6 or C-7 to give electron rich unsaturation, generates a radical at C 2 (carbohydrate numbering) which then undergoes efficient radical cyclization onto the pendant olefin to give the corresponding carbocycle.
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An expeditious entry to carbohydrate derived enynes and ene-diynes via Sonogashira coupling of halo-exo-glycals
TL;DR: In this article, a sonogashira coupling of bromo or iodo-exo-glycals, readily prepared from 1-Exo-methylene furanoses and pyranoses, provides an efficient entry to furanose- and Pyranose derived enyne and ene-diyne moieties found in biologically relevant structures.