J
J. Cristobal Lopez
Researcher at Spanish National Research Council
Publications - 168
Citations - 2439
J. Cristobal Lopez is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Radical cyclization & Glycosyl. The author has an hindex of 24, co-authored 168 publications receiving 2263 citations. Previous affiliations of J. Cristobal Lopez include North Carolina State University & Durham University.
Papers
More filters
Journal ArticleDOI
Synthesis of a 28-mer Oligosaccharide Core of Mycobacterial lipoarabinomannan (LAM) Requires only Two n-Pentenyl Orthoester Progenitors
TL;DR: The 28-mer, 93 (MW = 11122.54) is, as far as we are aware, the largest hetero-oligosaccharide that has been synthesized as discussed by the authors.
Journal ArticleDOI
Further Insight into “Matching” of Donors and Acceptors via Reciprocal Donor Acceptor Selectivity (RDAS) Studies
Abstract: Experiments with n-pentenyl glycosides and thioglycosides show that protecting groups have a dominant effect in controlling regioselective glycosidations whereby the best 'match' of donor with acceptor emerges. The experiments also show that for this outcome to be observed, the armed and disarmed donors must be allowed to compete on an equal level. If this condition is not met, coupling may still occur, but it will not be the best 'match'.
Journal ArticleDOI
The C4-exo methylene isomer of avermectin B1a: Synthesis via an allylic radical and bioactivity
TL;DR: Avermectin B1a Δ4,4a, 2, and its bioactivity evaluated in this article, where the key step of the transformation is the reduction of an intermediate allylic radical with nBu3SnH.
Journal ArticleDOI
Ferrier–Nicholas Cations from C-3-Alkynylglycals: Access to C-3-Branched Allylic Glycosides and Ring-Opening Derivatives
TL;DR: The authors of as mentioned in this paper are grateful to the Ministerio de Economia y Competitividad for grants CTQ2012-32114 and CTQ2015-66702-R. L. and S. M.