J
J. Dupuis
Researcher at University of Bedfordshire
Publications - 6
Citations - 511
J. Dupuis is an academic researcher from University of Bedfordshire. The author has contributed to research in topics: European union & Animal Use Alternatives. The author has an hindex of 5, co-authored 6 publications receiving 499 citations. Previous affiliations of J. Dupuis include Novartis.
Papers
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Journal ArticleDOI
The International EU/COLIPA In Vitro Phototoxicity Validation Study : Results of Phase II (Blind Trial). Part 1 : The 3T3 NRU Phototoxicity Test
Horst Spielmann,M. Balls,M. Balls,J. Dupuis,J. Dupuis,W.J. Pape,W.J. Pape,W.J. Pape,G. Pechovitch,G. Pechovitch,O. De Silva,O. De Silva,O. De Silva,H.-G. Holzhütter,H.-G. Holzhütter,H.-G. Holzhütter,R. Clothier,R. Clothier,R. Clothier,P. Desolle,P. Desolle,P. Desolle,Frank Gerberick,Frank Gerberick,Frank Gerberick,M. Liebsch,M. Liebsch,Will W. Lovell,Will W. Lovell,Th. Maurer,Th. Maurer,Th. Maurer,U. Pfannenbecker,U. Pfannenbecker,U. Pfannenbecker,J.M. Potthast,J.M. Potthast,J.M. Potthast,M. Csato,M. Csato,M. Csato,Dariusz Sladowski,Dariusz Sladowski,W. Steiling,W. Steiling,W. Steiling,P. Brantom,P. Brantom +47 more
TL;DR: A draft OECD Guideline for "In Vitro Phototoxicity Testing", incorporating the standard protocol of the 3T3 NRU PT test, will be submitted to the OECD test guidelines programme in due course.
Journal ArticleDOI
A summary report of the COLIPA international validation study on alternatives to the draize rabbit eye irritation test.
P. Brantom,L.H. Bruner,M. Chamberlain,O. de Silva,J. Dupuis,L.K. Earl,D.P. Lovell,W. J. W. Pape,M. Uttley,D.M. Bagley,F.W. Baker,M. Bracher,P. Courtellemont,L. Declercq,S. Freeman,W. Steiling,A.P. Walker,G.J. Carr,N. Dami,G. Thomas,John W. Harbell,Penny Jones,Uwe Pfannenbecker,Jacqueline Southee,M. Tcheng,H. Argembeaux,D. Castelli,Richard H. Clothier,David J. Esdaile,H. Itigaki,K. Jung,Y. Kasai,Hajime Kojima,U. Kristen,M. Larnicol,R.W. Lewis,K. D. Marenus,O. Moreno,A. Peterson,E.S. Rasmussen,C. Robles,M. Stern +41 more
TL;DR: Preliminary results indicate that none of the alternative methods evaluated could be confirmed as a valid replacement for the Draize eye irritation test across the full irritation scale.
Journal ArticleDOI
A Study on UV Filter Chemicals from Annex VII of European Union Directive 76/768/EEC, in the In Vitro 3T3 NRU Phototoxicity Test.
Horst Spielmann,M. Balls,J. Dupuis,W. J. W. Pape,O. de Silva,Hermann-Georg Holzhütter,Frank Gerberick,Manfred Liebsch,Will W. Lovell,Uwe Pfannenbecker +9 more
TL;DR: The management team and participants conclude that the 3T3 NRU PT test is a valid test for correctly assessing the phototoxic potential of UV filter chemicals, if the defined concentration limits are taken into account.
Book ChapterDOI
EEC/COLIPA in vitro Photoirritancy Program: Results of the First Stage of Validation1
Horst Spielmann,Manfred Liebsch,W. J. W. Pape,M. Balls,J. Dupuis,G. Klecak,Will W. Lovell,Th. Maurer,O. De Silva,W. Steiling +9 more
Journal Article
Development and validation of non-animal tests and testing strategies: the identification of a coordinated response to the challenge and the opportunity presented by the Sixth Amendment to the Cosmetics Directive (76/768/EEC)
M. Balls,W. de. Klerck,F.W. Baker,M. van. Beek,Claude Bouillon,L.H. Bruner,Jorgen Carstensen,Mark Chamberlain,M. Cottin,Rodger Curren,J. Dupuis +10 more