J
J H Scialfa
Researcher at University of São Paulo
Publications - 16
Citations - 245
J H Scialfa is an academic researcher from University of São Paulo. The author has contributed to research in topics: Melatonin & Pineal gland. The author has an hindex of 7, co-authored 15 publications receiving 210 citations.
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Journal ArticleDOI
Melatonin synthesis impairment as a new deleterious outcome of diabetes‐derived hyperglycemia
Fernanda Gaspar do Amaral,Ariane O. Turati,Mark Thomaz Ugliara Barone,J H Scialfa,Daniella do Carmo Buonfiglio,Rafael Peres,Rodrigo A. Peliciari-Garcia,Solange Castro Afeche,Larissa de Sá Lima,Cristoforo Scavone,Silvana Bordin,Russel J. Reiter,Luiz Menna-Barreto,José Cipolla-Neto +13 more
TL;DR: Evidence is provided that high circulating glucose levels interfere with pineal melatonin production in rats both in vivo and in vitro and that optimal glycemic control is usually an issue for patients with diabetes.
Journal ArticleDOI
Insulin modulates norepinephrine-mediated melatonin synthesis in cultured rat pineal gland.
Rodrigo Antonio Peliciari Garcia,Solange Castro Afeche,J H Scialfa,Fernanda Gaspar do Amaral,Sabrina Heloisa José dos Santos,Fábio Bessa Lima,Martin E. Young,José Cipolla-Neto +7 more
TL;DR: It is concluded that insulin potentiates NE-mediated melatonin synthesis in cultured rat pineal gland, potentially through post-transcriptional events.
Journal ArticleDOI
The effects of lesions of the thalamic intergeniculate leaflet on the pineal metabolism
José Cipolla-Neto,I Bartol,Patricia Monteiro Seraphim,Solange Castro Afeche,J H Scialfa,Ana Maria Peraçoli +5 more
TL;DR: The results suggest that the intergeniculate leaflet has a role in regulating the amplitude of the diurnal rhythm of pineal NAS production rather than its phase entrainment to light-dark cycle.
Journal ArticleDOI
Tryptophan hydroxylase is modulated by L-type calcium channels in the rat pineal gland
Roseli Barbosa,J H Scialfa,Ilza Campos Mingarini Terra,José Cipolla-Neto,Valérie Simonneaux,Solange Castro Afeche +5 more
TL;DR: It seems that the calcium influx through L-type high voltage-activated calcium channels is essential for the full activation of tryptophan hydroxylase leading to melatonin synthesis in the pineal gland.
Journal ArticleDOI
Ethanol consumption and pineal melatonin daily profile in rats.
Rafael Peres,Fernanda Gaspar do Amaral,Thiago Cardoso Madrigrano,J H Scialfa,Silvana Bordin,Solange Castro Afeche,José Cipolla-Neto +6 more
TL;DR: The results confirm the alterations in the daily melatonin profile of alcoholic rats and suggest the possible mechanisms for the observed melatonin synthesis modification.