J
J. Holmes
Publications - 15
Citations - 648
J. Holmes is an academic researcher. The author has contributed to research in topics: Optical coherence tomography & Blood flow. The author has an hindex of 10, co-authored 14 publications receiving 480 citations.
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Journal ArticleDOI
Dynamic Optical Coherence Tomography in Dermatology
Martina Ulrich,Lotte Themstrup,Nathalie De Carvalho,Marco Manfredi,Costantino Grana,Silvana Ciardo,Raphaela Kästle,J. Holmes,Richard Whitehead,Gregor B.E. Jemec,Giovanni Pellacani,Julia Welzel +11 more
TL;DR: Dynamic OCT (D-OCT) based on speckle variance OCT is of special interest as it allows the in vivo evaluation of blood vessels and their distribution within specific lesions, providing additional functional information and consequently greater density of data.
Journal ArticleDOI
Advances in optical coherence tomography in dermatology-a review.
TL;DR: OCT may be of value in diseases characterized with dynamic changes in the vasculature of the skin and the addition of functional measures is strongly encouraged, and OCT in dermatology is still an emerging technology that has great potential for improving further in the future.
Journal ArticleDOI
Imaging Blood Vessel Morphology in Skin: Dynamic Optical Coherence Tomography as a Novel Potential Diagnostic Tool in Dermatology
Sandra Schuh,J. Holmes,Martina Ulrich,Lotte Themstrup,Gregor B.E. Jemec,Nathalie De Carvalho,Giovanni Pellacani,Julia Welzel +7 more
TL;DR: The potential of D-OCT as a diagnostic tool in dermatology is examined and the ability to visualize and measure vessel morphology providing a new insight into healthy, inflammatory and neoplastic skin lesions such as malignant melanoma is examined.
Journal ArticleDOI
Validation of Dynamic optical coherence tomography for non-invasive, in vivo microcirculation imaging of the skin
Lotte Themstrup,Julia Welzel,S. Ciardo,R. Kaestle,Martina Ulrich,J. Holmes,Richard Whitehead,E. C Sattler,N. Kindermann,Giovanni Pellacani,Gregor B.E. Jemec +10 more
TL;DR: D-OCT was able to reliably image and identify changes in the skin vasculature consistent with the induced physiological blood flow changes and these basic findings support the use of D-O CT imaging for in vivo microcirculation imaging of the skin.
Journal ArticleDOI
In vivo micro-angiography by means of speckle-variance optical coherence tomography (SV-OCT) is able to detect microscopic vascular changes in naevus to melanoma transition.
N. De Carvalho,S. Ciardo,A. M. Cesinaro,Gregor B.E. Jemec,Martina Ulrich,Julia Welzel,J. Holmes,Giovanni Pellacani +7 more
TL;DR: Melanotan-associated melanoma in situ, a-MSH hormone analog in erythropoietic protoporphyria, and public health issues arising from sale of illegal and potentially unsafe ‘tanning chemicals’.