抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1（PfPMP1）与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用，在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员，通过启动转录不同的var基因变异体为抗原变异提供了分子基础。

疟原虫var基因转换速率变化导致抗原变异[英]／Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A

[신간의 별자리x] 우리/미술, 그리고 ‘슬픔의 박물관’

This is an updated version of supplementary information to accompany "Quantum supremacy using a programmable superconducting processor", an article published in the October 24, 2019 issue of Nature. The main article is freely available at this https URL. Summary of changes since arXiv:1910.11333v1 (submitted 23 Oct 2019): added URL for qFlex source code; added Erratum section; added Figure S41 comparing statistical and total uncertainty for log and linear XEB; new References [1,65]; miscellaneous updates for clarity and style consistency; miscellaneous typographical and formatting corrections.

/pdf/supplementary-information-for-quantum-supremacy-using-a-3tkhfafpzk.pdf

Supplementary information for "Quantum supremacy using a programmable superconducting processor"

The interaction of matter and light is one of the fundamental processes occurring in nature, and its most elementary form is realized when a single atom interacts with a single photon. Reaching this regime has been a major focus of research in atomic physics and quantum optics1 for several decades and has generated the field of cavity quantum electrodynamics2,3. Here we perform an experiment in which a superconducting two-level system, playing the role of an artificial atom, is coupled to an on-chip cavity consisting of a superconducting transmission line resonator. We show that the strong coupling regime can be attained in a solid-state system, and we experimentally observe the coherent interaction of a superconducting two-level system with a single microwave photon. The concept of circuit quantum electrodynamics opens many new possibilities for studying the strong interaction of light and matter. This system can also be exploited for quantum information processing and quantum communication and may lead to new approaches for single photon generation and detection.

https://arxiv.org/pdf/cond-mat/0407325.pdf

Strong coupling of a single photon to a superconducting qubit using circuit quantum electrodynamics

Topological photonics is a rapidly emerging field of research in which geometrical and topological ideas are exploited to design and control the behavior of light. Drawing inspiration from the discovery of the quantum Hall effects and topological insulators in condensed matter, recent advances have shown how to engineer analogous effects also for photons, leading to remarkable phenomena such as the robust unidirectional propagation of light, which hold great promise for applications. Thanks to the flexibility and diversity of photonics systems, this field is also opening up new opportunities to realize exotic topological models and to probe and exploit topological effects in new ways. This article reviews experimental and theoretical developments in topological photonics across a wide range of experimental platforms, including photonic crystals, waveguides, metamaterials, cavities, optomechanics, silicon photonics, and circuit QED. A discussion of how changing the dimensionality and symmetries of photonics systems has allowed for the realization of different topological phases is offered, and progress in understanding the interplay of topology with non-Hermitian effects, such as dissipation, is reviewed. As an exciting perspective, topological photonics can be combined with optical nonlinearities, leading toward new collective phenomena and novel strongly correlated states of light, such as an analog of the fractional quantum Hall effect.

Topological Photonics

Hybrid quantum circuits combine two or more physical systems, with the goal of harnessing the advantages and strengths of the different systems in order to better explore new phenomena and potentially bring about novel quantum technologies. This article presents a brief overview of the progress achieved so far in the field of hybrid circuits involving atoms, spins, and solid-state devices (including superconducting and nanomechanical systems). How these circuits combine elements from atomic physics, quantum optics, condensed matter physics, and nanoscience is discussed, and different possible approaches for integrating various systems into a single circuit are presented. In particular, hybrid quantum circuits can be fabricated on a chip, facilitating their future scalability, which is crucial for building future quantum technologies, including quantum detectors, simulators, and computers.

/pdf/hybrid-quantum-circuits-superconducting-circuits-interacting-52djng19hs.pdf

Hybrid quantum circuits: Superconducting circuits interacting with other quantum systems

Superconducting circuits based on Josephson junctions exhibit macroscopic quantum coherence and can behave like artificial atoms. Recent technological advances have made it possible to implement atomic-physics and quantum-optics experiments on a chip using these artificial atoms. This Review presents a brief overview of the progress achieved so far in this rapidly advancing field. We not only discuss phenomena analogous to those in atomic physics and quantum optics with natural atoms, but also highlight those not occurring in natural atoms. In addition, we summarize several prospective directions in this emerging interdisciplinary field.

Atomic physics and quantum optics using superconducting circuits

Superconducting circuits can behave like atoms making transitions between two levels. Such circuits can test quantum mechanics at macroscopic scales and be used to conduct atomic-physics experiments on a silicon chip.

Superconducting Circuits and Quantum Information

We investigate the quantum dynamics of a Cooper-pair box with a superconducting loop in the presence of a nonclassical microwave field. We demonstrate the existence of Rabi oscillations for both single- and multiphoton processes and, moreover, we propose a new quantum computing scheme (including one-bit and conditional two-bit gates) based on Josephson qubits coupled through microwaves.

https://link.aps.org/pdf/10.1103/PhysRevB.68.064509

Quantum information processing with superconducting qubits in a microwave field

We analyze the optical selection rules of the microwave-assisted transitions in a flux qubit superconducting quantum circuit (SQC) We show that the parities of the states relevant to the superconducting phase in the SQC are well defined when the external magnetic flux Phi(e)=Phi(0)/2; then the selection rules are the same as the ones for the electric-dipole transitions in usual atoms When Phi(e)not equal Phi(0)/2, the symmetry of the potential of the artificial "atom" is broken, a so-called Delta-type "cyclic" three-level atom is formed, where one- and two-photon processes can coexist We study how the population of these three states can be selectively transferred by adiabatically controlling the electromagnetic field pulses Different from Lambda-type atoms, the adiabatic population transfer in our three-level Delta atom can be controlled not only by the amplitudes but also by the phases of the pluses

https://dml.riken.jp/images/pub/nori/pdf/PRL_95_087001_Optical_Selection_Rules.pdf

J. Q. You

Papers

Hybrid quantum circuits: Superconducting circuits interacting with other quantum systems

Atomic physics and quantum optics using superconducting circuits

Superconducting Circuits and Quantum Information

Quantum information processing with superconducting qubits in a microwave field

Optical Selection Rules and Phase-Dependent Adiabatic State Control in a Superconducting Quantum Circuit