J
J. Venema
Researcher at VU University Amsterdam
Publications - 27
Citations - 2141
J. Venema is an academic researcher from VU University Amsterdam. The author has contributed to research in topics: Ribosomal RNA & 23S ribosomal RNA. The author has an hindex of 20, co-authored 27 publications receiving 2088 citations. Previous affiliations of J. Venema include European Bioinformatics Institute.
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Journal ArticleDOI
Ribosome synthesis in Saccharomyces cerevisiae.
J. Venema,David Tollervey +1 more
TL;DR: The recent, and often surprising, advances in the understanding of ribosome synthesis in the yeast Saccharomyces cerevisiae will underscore the unexpected complexity of eukaryotic ribosomes synthesis.
Journal ArticleDOI
Processing of pre-ribosomal RNA in Saccharomyces cerevisiae.
J. Venema,David Tollervey +1 more
TL;DR: The data that have led to the current picture of yeast pre‐rRNA processing are reviewed, mainly in the yeast Saccharomyces cerevisiae, and the underlying mechanisms are reviewed.
Journal ArticleDOI
RRP5 is required for formation of both 18S and 5.8S rRNA in yeast.
J. Venema,David Tollervey +1 more
TL;DR: A screen for mutations showing synthetic lethality with deletion of the non‐essential snoRNA, snR10, identified a novel gene, RRP5, which is essential for viability and encodes a 193 kDa nucleolar protein, suggesting that the critical function of Rrp5p is evolutionarily conserved.
Journal ArticleDOI
Separate structural elements within internal transcribed spacer 1 of Saccharomyces cerevisiae precursor ribosomal RNA direct the formation of 17S and 26S rRNA
R. W. Van Nues,Jeanet M.J. Rientjes,C. A. F. M. Van Der Sande,S. F. Zerp,C. Sluiter,J. Venema,Rudi J. Planta,Hendrik A. Raué +7 more
TL;DR: It is concluded that ITS1 is organized into two functionally and structurally distinct halves, suggesting two independent processing pathways for 26S rRNA formation.
Journal ArticleDOI
Evolutionarily conserved structural elements are critical for processing of Internal Transcribed Spacer 2 from Saccharomyces cerevisiae precursor ribosomal RNA.
R. W. Van Nues,Jeanet M.J. Rientjes,S.A. Morre,E. Mollee,Rudi J. Planta,J. Venema,Hendrik A. Raué +6 more
TL;DR: Structural features of Internal Transcribed Spacer 2 important for the correct and efficient removal of this spacer from Saccharomyces cerevisiae pre-rRNA were identified by in vivo mutational analysis based upon phylogenetic comparison with its counterparts from four different yeast species, suggesting a requirement for a higher-order structure of ITS2.