Jaber Emami

TL;DR: FDA guidance, development, evaluation, and validation of an IVIVC to grant biowaivers, and to set dissolution specifications for oral dosage forms, biopharmaceutics classification systems (BCS), BCS biowaIVERS, application of BCS inIVIVC development and concept of mapping are represented.

TL;DR: In this paper, the importance of albumin as a nanodrug delivery carrier for hydrophobic drugs, taking advantage of the passive as well as active targeting potential of this nanocarrier.

TL;DR: It was concluded that using PLGA with higher molecular weight, high surfactant and polymer concentrations led to a more appropriate encapsulation efficiency of insulin with low burst effect and desirable release pattern.

TL;DR: Pharmacokinetic parameters indicate that the developed GT formulation extended the pharmacokinetic profile achieved with CT, and the C(max)/MIC and AUC(0-∞)/MIC, which are indicative of eradication of pathogens, following co-administration of GT with CT were comparable to those of twice-daily administration of CT alone.

TL;DR: Size, zeta potential, entrapment efficiency, drug loading, and release percent of NLCs were measured and indicated that the most effective factors on the size were oleic acid content and surfactant percent.