Jacek Radwan

TL;DR: The genic capture hypothesis as discussed by the authors offers a resolution to the question of how genetic variation in male sexually selected traits is maintained in the face of strong female preferences, and it has been shown that male display traits are costly to produce and hence depend upon overall condition, which itself is dependent upon genes at many loci.

TL;DR: There is clearly a compelling need for data that would disclose the possible consequences of MHC diversity for population viability and before such evidence accumulates, captive breeding programs and other conservation measures aimed at inbreeding avoidance should be favoured over those protecting only MHC variation.

TL;DR: Mechanisms explaining landmark features of MHC genes: extreme polymorphism, excess of nonsynonymous changes in peptide-binding domains, and long gene genealogies are reviewed.

TL;DR: The parallel 454 sequencing can be an efficient genotyping platform for MHC and provides an alternative to classical genotypesing methods, and procedures to identify the threshold that can be used to reduce number of genotyped errors by eliminating most of artefactual alleles (AA).

TL;DR: The finding of two significant associations between MHC alleles and the intensity of the infection with the most prevalent nematode, Aspiculuris tetraptera, suggests that the directions of selection can differ between populations connected by a low level of gene flow, which may contribute to the maintenance of high DRB allele diversity.