PEEK Biomaterials in Trauma, Orthopedic, and Spinal Implants

Electromagnetic interference shielding effectiveness of carbon materials

Biomedical applications of polymer-composite materials: a review

Fundamentals of Materials Science

Biomaterials in total joint replacement.

Mechanical properties of soft human tissues under dynamic loading.

Computational and experimental models of the human torso for non-penetrating ballistic impact.

An orthopedic implant comprising a thermoplastic polymer or a composite comprising, in one embodiment, polyetheretherketone reinforced with 10% by volume of glass fibers, with an elastic modulus approximating the elastic modulus of bone A porous coating is formed on the implant surface by creating a roughness thereon, by coating the surface with hydroxyapatite or by embedding a biocompatible material such as titanium in the surface A two piece embodiment of the implant is joined and locked together, after the opposite ends of each piece are inserted in the medullary canal, using an interlocking mechanism comprising a fluted protrusion on one piece and a corresponding fluted cavity in the other piece with the fluted portions being complementarily tapered

Polymeric composite orthopedic implant

An isoelastic intramedullary implant has been developed using a composite of polyetheretherketone and 10% random, chopped E-glass fibers (GPEEK). The effect of this novel material on human bone cells has not been defined. The objective of this study was to test whether GPEEK supported the proliferation of the human bone cell line MG63, which exhibits osteoblastlike characteristics. Cells (1 × 105/mL) were propagated on GPEEK discs with three different surface roughnesses (3, 6, and 9 μm) and on polystyrene plates, for comparison. The reaction of MG63 osteoblastlike cells to the GPEEK polymer composite was analyzed by determination of cell yield, osteocalcin production, and levels of alkaline phosphatase. The viable cells that were retrieved from the GPEEK discs of all three surface roughness had an approximate sixfold increase in number. Osteoblastic function of the cells, indicated by osteocalcin production, was unimpaired after a 5-day culture on the three surfaces of GPEEK. The highest level of osteocalcin was produced by osteoblastic cells propagated on GPEEK with a 9-μm surface roughness. The levels of alkaline phosphatase of these cells were similarly greater for the different degrees of surface roughness. Overall, this study demonstrates that GPEEK supported proliferation of osteoblastlike cells and provided a favorable environment for the continued production of osteocalcin in vitro. © 1997 John Wiley & Sons, Inc. J Biomed Mater Res, 36, 137–144, 1997.

Glass peek composite promotes proliferation and osteocalcin production of human osteoblastic cells.

Fracture toughness, critical strain energy release rate, and critical stress intensity factor were determined for experimental and commercial restorative resins. A composite resin had lower resistance to crack initiation than an unfilled acrylic resin. The data were consistent with surface failure observed in single-pass wear studies of these resins.

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Jack C. Roberts

Papers

Mechanical properties of soft human tissues under dynamic loading.

Computational and experimental models of the human torso for non-penetrating ballistic impact.

Polymeric composite orthopedic implant

Glass peek composite promotes proliferation and osteocalcin production of human osteoblastic cells.

Fracture Toughness of Composite and Unfilled Restorative Resins