J
Jadranka Separovic
Researcher at University of Zagreb
Publications - 30
Citations - 1101
Jadranka Separovic is an academic researcher from University of Zagreb. The author has contributed to research in topics: Ranitidine & Cysteamine. The author has an hindex of 20, co-authored 30 publications receiving 1031 citations.
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The influence of a novel pentadecapeptide, BPC 157, on NG-nitro-l-arginine methylester and l-arginine effects on stomach mucosa integrity and blood pressure
Predrag Sikiric,Sven Seiwerth,Željko Grabarević,Rudolf Rucman,Marijan Petek,Vjekoslav Jagić,Branko Turkovic,Ivica Rotkvić,Stjepan Mise,Ivan Zoricic,Paško Konjevoda,Darko Perović,Ljubica Jurina,Jadranka Separovic,Miro Hanževački,Branka Artuković,Mirna Bratulić,Marina Tišljar,Miroslav Gjurašin,Pavle Miklić,Dinko Stančić-Rokotov,Zoran Slobodnjak,Nikola Jelovac,Anton Marovic +23 more
TL;DR: BPC 157 could interfere with the effects of NO on both gastric mucosal integrity and blood pressure maintenance in a specific way, especially with L-arginine, having a more prominent and/or particularly different effect from that of NO.
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The beneficial effect of BPC 157, a 15 amino acid peptide BPC fragment, on gastric and duodenal lesions induced by restraint stress, cysteamine and 96% ethanol in rats. A comparative study with H2 receptor antagonists, dopamine promotors and gut peptides
Predrag Sikiric,Sven Seiwerth,Zeljko Grabarevic,Marijan Petek,Rudolf Rucman,Branko Turkovic,Ivo Rotkvić,Vjekoslav Jagić,Marko Duvnjak,Stjepan Mise,Sanja Djacic,Jadranka Separovic,Marija Veljača,Ahmet Sallmani,Marko Banić,Tomislav Brkić +15 more
TL;DR: The protection of stomach and duodenum in conjecture with anti-inflammatory effect was demonstrated for a novel 15 amino acid peptide, coded BPC 157, a fragment of the recently discovered gastric juice peptide BPC, based on Monastral blue studies.
Journal ArticleDOI
A new gastric juice peptide, BPC. An overview of the stomach-stress-organoprotection hypothesis and beneficial effects of BPC
Predrag Sikiric,Marijan Petek,Rudolf Rucman,Sven Seiwerth,Zeljko Grabarevic,Ivo Rotkvić,Branko Turkovic,Vjekoslav Jagić,Boris Mildner,Marko Duvnjak,Nada Lang,Z. Danilović,A. Cviko,M. Kolega,Ahmet Sallmani,S. Djačić,Miljenko Bura,Tomislav Brkić,Marko Banić,Milan Dodig,V. Corić,Velimir N. Šimičević,Marija Veljača,Damir Erceg,Damir Ježek,L.J. Simunić-Banek,N. Skroza,Krešimir Bulić,Gojko Buljat,Miroslav Hanževački,V. Orihovac,Dražen Lučinger,Josip Čulig,Jadranka Separovic,Anton Marovic,Stjepan Mise,Ernest Suchanek,Wendy Matoz,Darko Perović,Miroslav Gjurašin,S. Mikulandra,K. Derniković,V. Cuk,I. Karakas +43 more
TL;DR: BPC, as a possible endogenous free radical scavenger and organoprotection mediator, could be a useful prototype of a new class of drugs, organoprotsective agents.
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Update of the Echocardiography Core Syllabus of the European Association of Cardiovascular Imaging (EACVI)
TL;DR: The update of the Echocardiography Core Syllabus of European Association of Cardiovascular Imaging (EACVI) is now available online.
Journal ArticleDOI
Beneficial effect of a novel pentadecapeptide BPC 157 on gastric lesions induced by restraint stress, ethanol, indomethacin, and capsaicin neurotoxicity
Predrag Sikiric,Sven Seiwerth,Zeljko Grabarevic,Rudolf Rucman,Marijan Petek,Vjekoslav Jagić,Branko Turkovic,Ivo Rotkvić,Stjepan Mise,Ivan Zoricic,Miroslav Gjurašin,Paško Konjevoda,Jadranka Separovic,Danica Galešić Ljubanović,Branka Artuković,Mirna Bratulić,Marina Tišljar,Ljubica Jurina,Gojko Buljat,Pavle Miklić,Anton Marovic +20 more
TL;DR: Analysis of gastroprotective effect of the pentadecapeptide BPC 157 on gastric lesions produced in rats by 96% ethanol, restraint stress, and indomethacin provides evidence for complex synergistic interaction between the beneficial effectiveness of B PC 157 and peptidergic sensory afferent neuron activity.