J
Jaime Pereira
Researcher at Pontifical Catholic University of Chile
Publications - 114
Citations - 3206
Jaime Pereira is an academic researcher from Pontifical Catholic University of Chile. The author has contributed to research in topics: Platelet & Platelet activation. The author has an hindex of 29, co-authored 114 publications receiving 2954 citations. Previous affiliations of Jaime Pereira include The Catholic University of America & University of Chile.
Papers
More filters
Journal ArticleDOI
Human platelets synthesize and express functional tissue factor
TL;DR: Human platelets not only assemble the clotting reactions on their membrane, but also supply their own TF for thrombin generation in a timely and spatially circumscribed process, which simplify, unify, and provide a more coherent formulation of the current cell-based model of hemostasis.
Journal ArticleDOI
Inflammation, not hyperhomocysteinemia, is related to oxidative stress and hemostatic and endothelial dysfunction in uremia.
Diego Mezzano,Edgar Pais,Eduardo Aranda,Olga Panes,Patricio Downey,Mireya Ortiz,Rodrigo Tagle,Fernando González,Teresa Quiroga,M. Soledad Caceres,Federico Leighton,Jaime Pereira +11 more
TL;DR: Systemic inflammation, which is closely associated with augmented oxidative stress, endothelial cell dysfunction and hemostatic activation, emerges as a major cardiovascular risk factor in CRF.
Journal ArticleDOI
Acute thrombocytopenia after treatment with tirofiban or eptifibatide is associated with antibodies specific for ligand-occupied GPIIb/IIIa.
Daniel W. Bougie,Peter R. Wilker,Elizabeth Wuitschick,Brian R. Curtis,Mohammad I. Malik,Stewart Levine,Richard N. Lind,Jaime Pereira,Richard H. Aster +8 more
TL;DR: The findings indicate that acute thrombocytopenia after the administration of tirofiban or eptifibatide can be caused by drug-dependent antibodies that are “naturally occurring” or are induced by prior exposure to drug.
Journal ArticleDOI
High prevalence of bleeders of unknown cause among patients with inherited mucocutaneous bleeding. A prospective study of 280 patients and 299 controls
Teresa Quiroga,Manuela Goycoolea,Olga Panes,Eduardo Aranda,Carlos Martinez,Sabine Belmont,B. Muñoz,Pamela Zúñiga,Jaime Pereira,Diego Mezzano +9 more
TL;DR: The results support the proposal that low plasma VWF levels, but also platelet function defects, should be considered risk factors rather than unequivocal causes of hemorrhages.
Journal ArticleDOI
Circulating platelet-derived microparticles in systemic lupus erythematosus. Association with increased thrombin generation and procoagulant state.
Jaime Pereira,Gino Alfaro,Manuela Goycoolea,Teresa Quiroga,Mauricio Ocqueteau,Loreto Massardo,Carol Pérez,Claudia G. Sáez,Olga Panes,Valeria Matus,Diego Mezzano +10 more
TL;DR: The increased number of circulating platelet-derived microparticles and their association with high ETP and activation of the coagulation system suggest that thesemicroparticles play an important role in the pathogenesis of the prothrombotic state in SLE patients.