Jaiprakash G. Shewale

TL;DR: Comparison of the physicochemical properties of purified enzyme preparations indicate a wide variation; however, in general the PVAs are specific for phenoxyacetyl amides of beta-lactam molecules and very few enzymes hydrolyze other phenoxy acetyl derivatives.

TL;DR: An extensive research program for isolation and studies on the mechanism of action of secondary metabolites has documented a wider group of compounds that are not antimicrobial agents that have potential to alleviate human and animal suffering and to protect plants from diseases.

TL;DR: Concentration and purification of the enzyme can be achieved in a single step for hydrophobic binding of penicillin amidase to modified Sepharose.

TL;DR: Beijerinckia indica var.penicillanicum mutant UREMS-5, producing 168% more penicillin V acylase, was obtained by successive treatment with UV, γ-irradiation and ethylmethane sulfonate.

TL;DR: A simple method based on Schiff’s base formation betweenp-dimethylaminobenzaldehyde and cephalosporin C is developed and the application of the method in monitoring bioconversion of cEPhalospora C to glutaryl-7-amino cep Halosporanic acid is described.