J
Jame R. Fuchs
Researcher at Ohio State University
Publications - 1
Citations - 289
Jame R. Fuchs is an academic researcher from Ohio State University. The author has contributed to research in topics: Curcumin & DNA hypomethylation. The author has an hindex of 1, co-authored 1 publications receiving 259 citations.
Papers
More filters
Journal ArticleDOI
Curcumin is a potent DNA hypomethylation agent.
Zhongfa Liu,Zhiliang Xie,William P. Jones,Ryan E. Pavlovicz,Shujun Liu,Jianhua Yu,Pui-Kai Li,Jiayuh Lin,Jame R. Fuchs,Guido Marcucci,Chenglong Li,Kenneth K. Chan +11 more
TL;DR: Curcumin inhibits the activity of M. SssI with an IC(50) of 30 nM, but no inhibitory activity of hexahydrocurcumin up to 100 microM, and can induce global DNA hypomethylation in a leukemia cell line.