James A. Talcott

TL;DR: The risk index accurately identifies patients at low risk for complications and may be used to select patients for testing therapeutic strategies that may be more convenient or cost-effective.

TL;DR: It is demonstrated that a shorter CAG repeat sequence in the androgen receptor gene predicts higher grade and advanced stage of prostate cancer at diagnosis, and metastasis and mortality from the disease.

TL;DR: Bilateral orchiectomy or luteinizing hormone-releasing hormone agonists are recommended initial androgen-deprivation treatments (ADTs) and data are insufficient to support use of intermittent androgen blockade outside clinical trials.

TL;DR: This risk assessment model accurately stratified the medical risk of cancer patients with fever and neutropenia using only clinical information available on the first day of their course and confirmed low-risk patients are an appropriate population in which to study less intensive treatment strategies.

TL;DR: It may be possible to assess the medical stability of patients with fever and neutropenia based on presenting clinical features to enable clinicians to identify groups of medically stable patients for whom conventional supportive care may be given safely under medical supervision of less intensity or of shorter duration than conventional treatment in the acute-care hospital setting.