James Geraghty

TL;DR: Patients without clinical involvement of the axilla should undergo sentinel-node biopsy routinely, and may be spared complete axillary dissection when the sentinel node is disease-free, and thereby provide important information about the status of axillary nodes.

TL;DR: In the large majority of patients with breast cancer, lymphoscintigraphy and γ-probe-guided surgery can be used to locate the sentinel node in the axilla, and thereby provide important information about the status of axillary nodes.

TL;DR: Before pretargeting strategies are applied clinically, a thorough understanding of these systems is required and forms the backbone of this report.

TL;DR: Vasen et al. as mentioned in this paper investigated the possibility that the site of the mutation in the adenomatous polyposis coli (APC) gene may assist in the choice of surgical procedure, and found that further surgery, needed for recurrent polyps or rectal cancer, was greater in patients with mutations in the region after codon 1250 than in those with mutations before this codon.

TL;DR: SN biopsy should be performed by surgeons and nuclear medicine doctors in co-operation, both methods being adopted simultaneously to reduce the percentage of procedure failures.