J
James Hooper
Researcher at Imperial College London
Publications - 35
Citations - 2778
James Hooper is an academic researcher from Imperial College London. The author has contributed to research in topics: Troponin T & Heart failure. The author has an hindex of 22, co-authored 35 publications receiving 2638 citations. Previous affiliations of James Hooper include National Institutes of Health.
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Journal ArticleDOI
Plasma Cytokine Parameters and Mortality in Patients With Chronic Heart Failure
Mathias Rauchhaus,Wolfram Doehner,Darrel P. Francis,Constantinos H. Davos,Michael Kemp,Christa Liebenthal,Josef Niebauer,James Hooper,Hans-Dieter Volk,Andrew J.S. Coats,Stefan D. Anker +10 more
TL;DR: Assessment of sT NF-R1 may be useful in identifying patients who are at high risk of death and in monitoring patients undergoing anti-TNF-alpha treatment, independent of established markers of CHF severity.
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Cytokines and neurohormones relating to body composition alterations in the wasting syndrome of chronic heart failure.
Stefan D. Anker,Piotr Ponikowski,Andrew L. Clark,Francisco Leyva,Mathias Rauchhaus,Michael Kemp,Mauro M. Teixeira,Paul G. Hellewell,James Hooper,P. A. Poole-Wilson,Andrew J.S. Coats +10 more
TL;DR: The levels of catabolic hormones and cytokines correlated significantly with reduced muscle and fat tissue content and reduced bone mass and peripheral loss of muscle tissue is a general finding in chronic heart failure.
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Ischaemic preconditioning reduces troponin T release in patients undergoing coronary artery bypass surgery
TL;DR: The direct application of a preconditioning stimulus in clinical practice has been shown, for the first time, to protect patients against irreversible myocyte injury.
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Deficient insulin-like growth factor I in chronic heart failure predicts altered body composition, anabolic deficiency, cytokine and neurohormonal activation.
J. Niebauer,Claus Dieter Pflaum,Andrew L. Clark,Christian J. Strasburger,James Hooper,Philip A. Poole-Wilson,Andrew J.S. Coats,Stefan D. Anker +7 more
TL;DR: Patients with low insulin-like growth factor I levels show signs of altered body composition, cytokine and neuroendocrine activation, to a greater extent than patients with normal/high levels.
Journal ArticleDOI
B-type natriuretic peptide concentrations in contemporary Eisenmenger syndrome patients: predictive value and response to disease targeting therapy
Gerhard-Paul Diller,Rafael Alonso-Gonzalez,Aleksander Kempny,Konstantinos Dimopoulos,Ryo Inuzuka,Georgios Giannakoulas,Lianne Castle,Astrid E. Lammers,James Hooper,Anselm Uebing,Lorna Swan,Michael A. Gatzoulis,Stephen J. Wort +12 more
TL;DR: BNP concentrations predict outcome in contemporary Eisenmenger patients and increases in BNP concentrations over time are also of prognostic significance, while treatment-naïve patients have static or rising B NP concentrations.