J
James Li
Researcher at University of Michigan
Publications - 3
Citations - 814
James Li is an academic researcher from University of Michigan. The author has contributed to research in topics: Medicine & Gene. The author has an hindex of 1, co-authored 1 publications receiving 749 citations.
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Journal ArticleDOI
An Integrated Network of Androgen Receptor, Polycomb, and TMPRSS2-ERG Gene Fusions in Prostate Cancer Progression
Jindan Yu,Jianjun Yu,Ram Shankar Mani,Qi Cao,Chad Brenner,Xuhong Cao,Xiaoju Wang,Longtao Wu,James Li,Ming Hu,Yusong Gong,Hong Cheng,Bharathi Laxman,Adaikkalam Vellaichamy,Sunita Shankar,Yong Li,Saravana M. Dhanasekaran,Roger Morey,Terrence R. Barrette,Robert J. Lonigro,Scott A. Tomlins,Sooryanarayana Varambally,Zhaohui S. Qin,Arul M. Chinnaiyan +23 more
TL;DR: These findings provide a working model in which TMPRSS2-ERG plays a critical role in cancer progression by disrupting lineage-specific differentiation of the prostate and potentiating the EZH2-mediated dedifferentiation program.
Journal ArticleDOI
Formalin Fixation, Delay to Fixation, and Time in Fixative Adversely Impact Copy Number Variation Analysis by aCGH.
James Li,Sarah R. Greytak,Ping Guan,Kelly B. Engel,David Goerlitz,Md. Mofazzal Dr. Shahidul Islam,Rency S. Varghese,Helen M. Moore,Habtom W. Ressom +8 more
TL;DR: Effects were not random as a higher guanine-cytosine (GC) content and/or a higher percentage of repeats were observed among stable regions, and limiting aCGH analysis to FFPE specimens with a DTF <3 hours and a TIF <72 hours may circumvent some effects.
Journal ArticleDOI
Susceptibility of female rats to cardiac arrhythmias following refeeding after severe food restriction
Aline M. A. de Souza,Jônathas Fernandes Queiroz de Almeida,Nataliia V. Shults,Hong Ji,James Li,V. Sandberg +5 more
TL;DR: In this paper , the authors studied cardiac morphology and function in female (F) and male (M) severe food restricted rats 3 months after refeeding (sFR-Refed).