J
James R. Scherer
Researcher at University of California, Berkeley
Publications - 52
Citations - 3866
James R. Scherer is an academic researcher from University of California, Berkeley. The author has contributed to research in topics: Raman spectroscopy & Capillary electrophoresis. The author has an hindex of 30, co-authored 52 publications receiving 3747 citations. Previous affiliations of James R. Scherer include Affymetrix & University of California.
Papers
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Journal ArticleDOI
Radial Capillary Array Electrophoresis Microplate and Scanner for High-Performance Nucleic Acid Analysis
Yining Shi,Peter C. Simpson,James R. Scherer,David B. Wexler,Christine F. Skibola,Martyn T. Smith,Richard A. Mathies +6 more
TL;DR: The feasibility of performing high-throughput genotyping separations with capillary array electrophoresis microplates is established and the practical utility and multicolor detection capability is demonstrated by analyzing 96 methylenetetrahydrofolate reductase alleles in parallel using a noncovalent 2-color staining method.
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Integrated portable genetic analysis microsystem for pathogen/infectious disease detection.
Eric T. Lagally,James R. Scherer,Robert G. Blazej,Nicholas Toriello,Binh An Diep,M Ramchandani,George F. Sensabaugh,Lee W. Riley,Richard A. Mathies +8 more
TL;DR: This integrated portable genomic analysis microsystem demonstrates the feasibility of performing rapid high-quality detection of pathogens and their antimicrobial drug resistance by performing pathogen detection and genotyping directly from whole Escherichia coli and Staphylococcus aureus cells.
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Raman spectra and structure of water from -10 to 90.deg.
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High throughput DNA sequencing with a microfabricated 96-lane capillary array electrophoresis bioprocessor.
TL;DR: The μCAE system demonstrated here produces sequencing data at a 5-fold increase over current commercial capillary array electrophoresis technology, which permits lower reagent volumes and lower sample concentrations, and it presents numerous possibilities for integrated sample preparation and handling.
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Development and evaluation of a microdevice for amino acid biomarker detection and analysis on Mars
Alison M. Skelley,James R. Scherer,Andrew D. Aubrey,William H. Grover,Robin H. C. Ivester,Pascale Ehrenfreund,Frank J. Grunthaner,Jeffrey L. Bada,Richard A. Mathies +8 more
TL;DR: Field tests of the MOA successfully detected amino acids at 70 parts per trillion to 100 parts per billion in jarosite, a sulfate-rich mineral associated with liquid water that was recently detected on Mars.