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Eric T. Lagally
Researcher at University of California, Berkeley
Publications - 14
Citations - 2792
Eric T. Lagally is an academic researcher from University of California, Berkeley. The author has contributed to research in topics: Capillary electrophoresis & genomic DNA. The author has an hindex of 9, co-authored 14 publications receiving 2731 citations. Previous affiliations of Eric T. Lagally include University of California & University of California, San Francisco.
Papers
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Journal ArticleDOI
Single-molecule DNA amplification and analysis in an integrated microfluidic device.
TL;DR: This device demonstrates the most sensitive PCR possible in a microfabricated device and will also facilitate single-cell and single-molecule studies to expose the genetic variation underlying ensemble sequence and expression averages.
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Monolithic membrane valves and diaphragm pumps for practical large-scale integration into glass microfluidic devices
TL;DR: In this paper, elastomer membrane valves and diaphragm pumps suitable for large-scale integration into glass microfluidic analysis devices are fabricated and characterized, and a three-layer valve and pump design features simple non-thermal device bonding and a hybrid glass-PDMS fluidic channel.
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Monolithic integrated microfluidic DNA amplification and capillary electrophoresis analysis system
TL;DR: In this paper, a monolithic integrated DNA analysis system comprised of microfluidic valves and vents, PCR amplification chambers, and capillary electrophoretic separation channels has been microfabricated in a glass sandwich structure.
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Fully integrated PCR-capillary electrophoresis microsystem for DNA analysis
TL;DR: A fully integrated genomic analysis microsystem including microfabricated heaters, temperature sensors, and PCR chambers directly connected to capillary electrophoretic separation channels has been constructed and successful sex determination using a multiplex PCR reaction from human genomic DNA is demonstrated.
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Integrated portable genetic analysis microsystem for pathogen/infectious disease detection.
Eric T. Lagally,James R. Scherer,Robert G. Blazej,Nicholas Toriello,Binh An Diep,M Ramchandani,George F. Sensabaugh,Lee W. Riley,Richard A. Mathies +8 more
TL;DR: This integrated portable genomic analysis microsystem demonstrates the feasibility of performing rapid high-quality detection of pathogens and their antimicrobial drug resistance by performing pathogen detection and genotyping directly from whole Escherichia coli and Staphylococcus aureus cells.