J
Jan Hoffmann
Researcher at King's College London
Publications - 70
Citations - 2744
Jan Hoffmann is an academic researcher from King's College London. The author has contributed to research in topics: Migraine & Calcitonin gene-related peptide. The author has an hindex of 20, co-authored 64 publications receiving 1886 citations. Previous affiliations of Jan Hoffmann include University of Bern & Wellcome Trust.
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Journal ArticleDOI
Pathophysiology of Migraine: A Disorder of Sensory Processing
Peter J. Goadsby,Philip R. Holland,Margarida Martins-Oliveira,Jan Hoffmann,Christoph J. Schankin,Simon Akerman +5 more
TL;DR: Investment in understanding migraine leaves us at a new dawn, able to transform its impact on a global scale, as well as understand fundamental aspects of human biology.
Journal ArticleDOI
Diagnosis, pathophysiology, and management of cluster headache.
Jan Hoffmann,Arne May +1 more
TL;DR: Monoclonal antibodies against calcitonin gene-related peptide, a crucial neurotransmitter of the trigeminal system, are under investigation for the preventive treatment of cluster headache and will increase the understanding of the disorder and perhaps reveal other therapeutic targets.
Journal ArticleDOI
In vivo viscoelastic properties of the brain in normal pressure hydrocephalus.
Kaspar Josche Streitberger,Edzard Wiener,Jan Hoffmann,Jan Hoffmann,Florian Baptist Freimann,Dieter Klatt,Jürgen Braun,Kui Lin,Joyce R. McLaughlin,Christian Sprung,Randolf Klingebiel,Ingolf Sack +11 more
TL;DR: Viscoelastic constants related to the stiffness and micromechanical connectivity of brain tissue were derived from the dynamics of storage and loss moduli within the experimentally achieved frequency range of 25–62.5 Hz, demonstrating distinct tissue degradation associated with NPH.
Journal ArticleDOI
European Headache Federation guideline on idiopathic intracranial hypertension
Jan Hoffmann,Susan P Mollan,Koen Paemeleire,Christian Lampl,Rigmor Jensen,Alexandra J Sinclair +5 more
TL;DR: This European Headache Federation consensus paper provides evidence-based recommendations and practical advice on the investigation and management of IIH.
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Effect of Infusion of Calcitonin Gene-Related Peptide on Cluster Headache Attacks: A Randomized Clinical Trial.
Anne Luise Haulund Vollesen,Agneta Snoer,Rasmus P Beske,Song Guo,Jan Hoffmann,Rigmor Jensen,Messoud Ashina +6 more
TL;DR: Results suggest anti-CGRP drugs may be effective in cluster headache management and suggest patients with episodic cluster headaches reported attacks after CGRP or placebo but not in remission-phase episodic clusters headache.