Jan W. Dallinga

TL;DR: The currently available methodologies regarding sampling, sample analysis and data processing as well as their advantages and potential drawbacks are described and different application possibilities of VOC profiling are discussed.

TL;DR: Focusing on the subgroup of men with normal semen quality showed that sperm count and sperm progressive motility were inversely related to the concentrations of PCB metabolites within this group, the first time that a correlation between exposure to environmental pollutants with endocrine-disrupting capacity and human sperm quality has been observed.

TL;DR: In this paper, the authors developed a methodological approach able to identify profiles of VOCs in breath unique for patient groups and applied this recently developed methodology regarding diagnosis of COPD patients.

TL;DR: The current state of the art in data pre-processing and multivariate analysis of breathomics data is described and the community is made aware of the existing data fusion methods, as yet unresearched in breathomics.

TL;DR: It is concluded that metabolomics of VOCs in exhaled breath was possible in a reproducible way and was able to discriminate not only between CF patients and controls but also betweenCF patients with or without Pseudomonas colonization.