J
Jana Chládková
Researcher at Academy of Sciences of the Czech Republic
Publications - 10
Citations - 372
Jana Chládková is an academic researcher from Academy of Sciences of the Czech Republic. The author has contributed to research in topics: Base pair & DNA. The author has an hindex of 8, co-authored 10 publications receiving 361 citations.
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Guanine tetraplex topology of human telomere DNA is governed by the number of (TTAGGG) repeats
TL;DR: With an increasing repeat number, the fragment tetraplexes surprisingly are ever less thermostable and their migration and enthalpy decrease indicate increasing irregularities or domain splitting in their arrangements.
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Mapping the B-A conformational transition along plasmid DNA
TL;DR: The present method complements the previous methods used to study the B-A transition and can be employed to analyze multikilobase regions of genomic DNA whose restriction endonuclease cleavage fragments can be separated and quantified on agarose gels.
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Aqueous trifluorethanol solutions simulate the environment of DNA in the crystalline state
TL;DR: Spermine and magnesium or calcium cations promoted or suppressed the TFE-induced changes of several fragments to indicate that the crystallisation agents can decide which of the possible structures is adopted by the DNA fragment in the crystal.
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Conserved guanine-guanine stacking in tetraplex and duplex DNA
TL;DR: The results reveal that guanine-guanine stacking is a structural invariant conserved in various nucleic acid conformers and is likely to cohere with evolution of the genetic molecules and be important for fundamental functions, e.g. initiation of transcription.
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Comparison of the solution and crystal conformations of (G + C)-rich fragments of DNA
Michaela Vorlíčková,Juan A. Subirana,Jana Chládková,I. Tejralová,T. Huynh-Dinh,Luboš Arnold,Jaroslav Kypr +6 more
TL;DR: The present results indicate that the crystal double helices of DNA are stable in aqueous TFE rather than aqueously solution.