J
Jane Bayani
Researcher at University Health Network
Publications - 15
Citations - 1711
Jane Bayani is an academic researcher from University Health Network. The author has contributed to research in topics: Comparative genomic hybridization & Cytogenetics. The author has an hindex of 13, co-authored 15 publications receiving 1595 citations.
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Journal ArticleDOI
Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens.
Steven M. Pollard,Koichi Yoshikawa,Ian D. Clarke,Davide Danovi,Stefan H. Stricker,Roslin Russell,Jane Bayani,Renee Head,Marco Lee,Mark Bernstein,Jeremy A. Squire,Austin Smith,Peter B. Dirks +12 more
TL;DR: Routine and efficient derivation of adherent cell lines from malignant glioma that display stem cell properties and initiate high-grade gliomas following xenotransplantation are demonstrated.
Journal ArticleDOI
Genomic mechanisms and measurement of structural and numerical instability in cancer cells
Jane Bayani,Shamini Selvarajah,Georges Maire,Bisera Vukovic,Khaldoun Al-Romaih,Maria Zielenska,Jeremy A. Squire,Jeremy A. Squire +7 more
TL;DR: This work proposes the term structural chromosomal instability [(S)-CIN] to distinguish numerical from structural CIN, and describes the excessive rate of numerical and structural genomic change in tumors.
Journal ArticleDOI
Molecular cytogenetic analysis of medulloblastomas and supratentorial primitive neuroectodermal tumors by using conventional banding, comparative genomic hybridization, and spectral karyotyping.
Jane Bayani,Maria Zielenska,Paula Marrano,Yim Kwan Ng,Michael D. Taylor,Venita Jay,James T. Rutka,Jeremy A. Squire +7 more
TL;DR: A retrospective analysis of 19 medulloblastomas and five PNET cases studied using combinations of classic banding analysis, FISH, CGH, and SKY to examine comprehensively the chromosomal aberrations present in this tumor group and to attempt to identify common structural rearrangement(s).
Journal Article
Parallel Analysis of Sporadic Primary Ovarian Carcinomas by Spectral Karyotyping, Comparative Genomic Hybridization, and Expression Microarrays
Jane Bayani,James D. Brenton,Pascale F. Macgregor,Ben Beheshti,Monique Albert,Dhani Nallainathan,Jana Karaskova,Barry P. Rosen,Joan Murphy,Stephanie Laframboise,Brent W. Zanke,Jeremy A. Squire +11 more
TL;DR: It is demonstrated that SKY, CGH, and microarray analysis can in combination identify significantly smaller subsets of differentially expressed genes for future studies.
Journal ArticleDOI
Profiling genomic copy number changes in retinoblastoma beyond loss of RB1.
Ella Bowles,Timothy W. Corson,Timothy W. Corson,Jane Bayani,Jeremy A. Squire,Jeremy A. Squire,Nathalie Wong,Paul B.S. Lai,Brenda L. Gallie +8 more
TL;DR: Novel high‐level amplification of 1q32.1 in one primary tumor, confirmed by fluorescence in situ hybridization, strongly supports the presence of oncogene(s) in this region, possibly the mitotic kinesin, KIF14.