J
Jane Christopher-Hennings
Researcher at South Dakota State University
Publications - 111
Citations - 6776
Jane Christopher-Hennings is an academic researcher from South Dakota State University. The author has contributed to research in topics: Porcine reproductive and respiratory syndrome virus & Virus. The author has an hindex of 45, co-authored 109 publications receiving 6228 citations. Previous affiliations of Jane Christopher-Hennings include Center for Infectious Disease Research and Policy & Kansas State University.
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Journal ArticleDOI
Differentiation of U.S. and European isolates of porcine reproductive and respiratory syndrome virus by monoclonal antibodies.
Eric A. Nelson,Jane Christopher-Hennings,T. W. Drew,G Wensvoort,James E. Collins,David A. Benfield +5 more
TL;DR: Monoclonal antibodies to two U.S. isolates of porcine reproductive and respiratory syndrome (PRRS) virus indicate that PRRS viruses contain both conserved and divergent epitopes on the 15-kDa viral protein.
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A 10-kDa structural protein of porcine reproductive and respiratory syndrome virus encoded by ORF2b.
Wai-Hong Wu,Ying Fang,Rachel Farwell,Melissa Steffen-Bien,Raymond R.R. Rowland,Jane Christopher-Hennings,Eric A. Nelson +6 more
TL;DR: Results suggest that the 2b protein is virion associated and the principal product of ORF2, the major structural proteins of porcine reproductive and respiratory syndrome virus.
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Assessment of the efficacy of commercial porcine reproductive and respiratory syndrome virus (PRRSV) vaccines based on measurement of serologic response, frequency of gamma-IFN-producing cells and virological parameters of protection upon challenge.
Federico A. Zuckermann,Esther García,Ivan Diaz Luque,Jane Christopher-Hennings,Alan R. Doster,Monica Brito,Fernando A. Osorio +6 more
TL;DR: The results obtained indicate that the modified live virus vaccine was the only type of vaccine capable of establishing protective immunity, as measured by viral load in blood and tissues.
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Porcine reproductive and respiratory syndrome virus: a persistent infection.
Robert W. Wills,J. J. Zimmerman,Kyoung-Jin Yoon,Sabrina L. Swenson,M.J. McGinley,Howard T. Hill,Kenneth B. Platt,Jane Christopher-Hennings,Eric A. Nelson +8 more
TL;DR: Direct evidence of persistent PRRSV infection was shown in experimentally infected pigs by isolation of virus from oropharyngeal samples for up to 157 days after challenge and field observations of long-term herd infection and transmission via purchase of clinically normal, butPRRSV infected, animals were explained.
Journal ArticleDOI
Pathogenesis of Porcine Reproductive and Respiratory Syndrome Virus Infection in Gnotobiotic Pigs
Kurt Rossow,James E. Collins,Sagar M. Goyal,Eric A. Nelson,Jane Christopher-Hennings,David A. Benfield +5 more
TL;DR: Results of this experiment indicate that PRRSV is a multisystem disease characterized initially by viremia with subsequent virus distribution and replication in multiple organs causing interstitial pneumonia, vasculitis, lymphadenopathy, myocarditis, and encephalitis.