scispace - formally typeset
Search or ask a question

Showing papers by "Jane M. Andrews published in 1998"


Journal ArticleDOI
TL;DR: Results suggest that when infused to result in plasma concentrations slightly above usual postprandial concentrations, insulin does not inhibit its own release and the effects of intraduodenal glucose on appetite may be mediated through the release of GLP-1 and not insulin.

136 citations


Journal ArticleDOI
TL;DR: It is concluded that meal volume has a major effect on gastric emptying; in contrast posture has only a minor impact on intragastric meal distribution, which is observed only after a large meal, and no effect on stomach emptying.
Abstract: The effects of volume and posture on gastric emptying and intragastric distribution of a solid meal and appetite were evaluated. Eight normal volunteers were studied on four occasions, on each of w...

77 citations


Journal ArticleDOI
TL;DR: It is concluded that "physiological" hyperglycemia modifies gastric motor and sensory function and that synergy exists between blood glucose concentration and small intestinal nutrients in modulating gastric motility and appetite.
Abstract: We evaluated the effects of varying blood glucose concentration within the normal postprandial range and its interaction with small intestinal nutrients on antropyloric motility and appetite. Eight...

41 citations


Journal ArticleDOI
TL;DR: It is concluded that in healthy young males 1) intraduodenal infusion of lipid is a more potent stimulus of phasic pyloric motility and suppresses appetite more than intradeudenal glucose and 2) dietary glucose supplementation alters both the appetite suppressant effect of intrad UODenal lipid and the pylric motor response to intradUodinal glucose infusion.
Abstract: The effects of different macronutrients on appetite and pyloric motility and the impact of short-term dietary glucose supplementation on these responses were evaluated. Ten males (aged 19–38 yr) re...

31 citations