Janet A. Frohlich

TL;DR: Tenofovir in a vaginal gel formulation shows significant protection against HIV infection in a randomized control trial, and could potentially fill an important HIV prevention gap, especially for women unable to successfully negotiate mutual monogamy or condom use.

TL;DR: The authors argue that there have been few systematic attempts to determine the effectiveness of community engagement in research.

TL;DR: Men who initiate sex before age 15 form a distinct risk group in this setting and specific interventions are needed for young men in the preteen years, before sexual debut.

TL;DR: HIV incidence rates are devastatingly high in young women in rural and urban KwaZulu-Natal, despite reports of stabilized HIV prevalence observed in current surveillance data, highlighting the urgent need to enhance HIV prevention and treatment modalities.

TL;DR: Examination of partnership dynamics and characteristics in the context of HIV risk, including number of partners, age differences, partnership duration and concurrency, and frequency of contact among young people aged 15-24 in rural KwaZulu-Natal, South Africa, finds fluid partnership patterns are an important feature of young people's sexual risk in thecontext of South Africa's severe HIV epidemic.