J
Janet Beckmann
Researcher at Goethe University Frankfurt
Publications - 7
Citations - 747
Janet Beckmann is an academic researcher from Goethe University Frankfurt. The author has contributed to research in topics: Inflammation & Proteoglycan. The author has an hindex of 7, co-authored 7 publications receiving 658 citations.
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Journal ArticleDOI
Signaling by the matrix proteoglycan decorin controls inflammation and cancer through PDCD4 and MicroRNA-21.
Rosetta Merline,Kristin Moreth,Janet Beckmann,Madalina V. Nastase,Jinyang Zeng-Brouwers,José Guilherme Tralhão,Patricia Lemarchand,Josef Pfeilschifter,Roland M. Schaefer,Renato V. Iozzo,Liliana Schaefer +10 more
TL;DR: Decorin was an early response gene evoked by septic inflammation, and protein concentrations of decorin were increased in the plasma of septic patients and mice, and this pathway operates in both pathogen-mediated and sterile inflammation.
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Subunit composition and pigmentation of fucoxanthin-chlorophyll proteins in diatoms: evidence for a subunit involved in diadinoxanthin and diatoxanthin binding.
TL;DR: It is concluded that the enhanced content of diatoxanthin in FCPa plays a protective role, which is paralleled by a weakened light harvesting function due to a smaller amount of fucoxanthin.
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Role of Nox4 in murine models of kidney disease
Andrea Babelova,Despina Avaniadi,Oliver Jung,Christian Fork,Janet Beckmann,Judith Kosowski,Norbert Weissmann,Narayana Anilkumar,Ajay M. Shah,Liliana Schaefer,Katrin Schröder,Ralf P. Brandes +11 more
TL;DR: First in vivo data of the kidney do not support the view that Nox4 is a main driver of renal disease, and it rather appears that under specific conditions Nox 4 may even slightly limit injury and disease progression.
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De novo expression of circulating biglycan evokes an innate inflammatory tissue response via MyD88/TRIF pathways.
Jinyang Zeng-Brouwers,Janet Beckmann,Madalina-Viviana Nastase,Renato V. Iozzo,Liliana Schaefer +4 more
TL;DR: The results provide the first evidence that biglycan differentially triggers chemoattraction of leukocytes via two independent pathways, both under the control of TLR2/4, utilizing either MyD88 or TRIF adaptor proteins.
Journal ArticleDOI
CXCL16 and oxLDL are induced in the onset of diabetic nephropathy.
Paul Gutwein,Mohamed S. Abdel-Bakky,Kai Doberstein,Anja Schramme,Janet Beckmann,Liliana Schaefer,Kerstin Amann,Anke Doller,Nicole Kämpfer-Kolb,Abdel-Aziz H. Abdel-Aziz,El Sayed M. El Sayed,Josef Pfeilschifter +11 more
TL;DR: Regulation of CXCL16, ADAM10 and oxLDL expression may be an early event in the onset of DN and therefore all three proteins may represent potential new targets for diagnosis and therapeutic intervention in DN.