J
Janina Schoen
Researcher at University of Erlangen-Nuremberg
Publications - 9
Citations - 90
Janina Schoen is an academic researcher from University of Erlangen-Nuremberg. The author has contributed to research in topics: Medicine & Neutrophil extracellular traps. The author has an hindex of 1, co-authored 3 publications receiving 33 citations.
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Book ChapterDOI
Transcriptional control of dendritic cell development and functions.
TL;DR: Similarities, but also varieties, between human and murine DC subpopulations are challenging, and will require further investigation of human specimens under consideration of the influence of the tissue micromilieu and DC subset localization in the future.
Journal ArticleDOI
Neutrophils Orchestrate the Periodontal Pocket
Ljubomir Vitkov,Ljubomir Vitkov,Luis E. Muñoz,Janina Schoen,Jasmin Knopf,Bernd Minnich,Christine Schauer,Martin Herrmann,Matthias Hannig +8 more
TL;DR: In this paper, the authors show that injecting lipopolysaccharide (LPS) alone causes an exaggerated neutrophil response sufficient to precipitate experimental periodontitis, and that increased neutrophils responsiveness can effectuate gingiva damage likewise.
Journal ArticleDOI
Hypoxia Promotes Neutrophil Survival After Acute Myocardial Infarction
Maximilian Dölling,M. Eckstein,Jeeshan Singh,Christine Schauer,Janina Schoen,Xiaomei Shan,Aline Bozec,Jasmin Knopf,Georg Schett,Luis E. Muñoz,Martin Herrmann +10 more
TL;DR: It is concluded that nuclear HIF-1α is associated with prolonged neutrophil survival and enhanced oxidative stress in hypoxic areas of AMI.
Journal ArticleDOI
Neutrophils’ Extracellular Trap Mechanisms: From Physiology to Pathology
Janina Schoen,Maximilien Euler,Christine Schauer,Georg Schett,Martin Herrmann,Jasmin Knopf,Kursat Oguz Yaykasli +6 more
TL;DR: This review focusses on the understanding of NETs from their formation to their functions in both physiological and pathological processes as well as their role in pathogen uptake and clearance.
Journal ArticleDOI
Periodontitis-Derived Dark-NETs in Severe Covid-19
Ljubomir Vitkov,Jasmin Knopf,Jelena Krunic,Christine Schauer,Janina Schoen,Bernd Minnich,Matthias Hannig,Martin Herrmann +7 more
TL;DR: The role of propensity for increased NET formation, DNase I deficiency and low-grade endotoxaemia in periodontitis as aggravating factors for the severe course of COVID-19 is discussed and possible strategies for the diminution of increased levels of circulatingperiodontitis-derived NETs in CO VID-19 with periodentitis comorbidity are discussed.