J
Jason Ioannidis
Researcher at University of Edinburgh
Publications - 17
Citations - 342
Jason Ioannidis is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Heterogametic sex & Ovary. The author has an hindex of 9, co-authored 16 publications receiving 229 citations. Previous affiliations of Jason Ioannidis include Scotland's Rural College.
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Circulating miRNA signatures of early pregnancy in cattle.
TL;DR: Through genome-wide analyses, this study has successfully profiled plasma miRNA populations associated with early pregnancy in cattle and identified miR-26a as a potential circulating biomarker of early pregnancy.
Journal ArticleDOI
Primary sex determination in birds depends on DMRT1 dosage, but gonadal sex does not determine adult secondary sex characteristics.
Jason Ioannidis,Gunes Taylor,Debiao Zhao,Long Liu,Alewo Idoko-Akoh,Daoqing Gong,Robin Lovell-Badge,Silvana Guioli,Michael J. McGrew,Michael Clinton +9 more
TL;DR: In this article, the authors used a CRISPR-Cas9-based mono-allelic targeting approach and sterile surrogate hosts to generate birds with targeted mutations in the Mab-3-Related Transcription Factor 1 (DMRT1) gene.
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Circulating microRNA Profiles during the Bovine Oestrous Cycle
TL;DR: The results reveal the dynamic nature of plasma miRNAs during the oestrous cycle and provide evidence of the feasibility of using circulating miRNA profiles as biomarkers of reproductive function in livestock in the future.
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The adequate corpus luteum: miR-96 promotes luteal cell survival and progesterone production
TL;DR: In this article, the effects of specific miRNAs on survival and steroid production by human luteinized granulosa cells (hLGCs) were tested using specific miRNA inhibitors.
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Changes in circulating microRNA levels can be identified as early as day 8 of pregnancy in cattle
TL;DR: In this article, small RNA sequencing was used to identify 77 miRNAs that were differentially expressed on Day 60 relative to Day 0 of pregnancy, and selected 14 miRNA for validation by RT-qPCR.