J
Jean-Francois Patoiseau
Publications - 51
Citations - 541
Jean-Francois Patoiseau is an academic researcher. The author has contributed to research in topics: Alkyl & Trifluoromethyl. The author has an hindex of 10, co-authored 51 publications receiving 516 citations.
Papers
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Journal ArticleDOI
Immunological Quantitation and Localization of ACAT-1 and ACAT-2 in Human Liver and Small Intestine
Catherine C.Y. Chang,Naomi Sakashita,Kim Ornvold,Oneil Lee,Ellen T. Chang,Ruhong Dong,Song Lin,Chi-Yu Gregory Lee,Stephen C. Strom,Randeep Kashyap,John J. Fung,Robert V. Farese,Jean-Francois Patoiseau,Andre Delhon,Ta-Yuan Chang +14 more
TL;DR: The results collectively suggest that in humans, ACAT-2 performs significant catalytic roles in the fetal liver and in intestinal enterocytes.
Journal ArticleDOI
Human adipocyte fatty acid-binding protein (aP2) gene promoter-driven reporter assay discriminates nonlipogenic peroxisome proliferator-activated receptor gamma ligands.
Yves Rival,Aline Stennevin,Laurence Puech,Anne Rouquette,Claudie Cathala,Fabrice Lestienne,Elisabeth Dupont-Passelaigue,Jean-Francois Patoiseau,Thierry Wurch,Didier Junquero +9 more
TL;DR: Data characterized a functional promoter of the human aP2 gene; its in vitro pharmacological regulation in PPARγ-mediated reporter-gene assay may represent an interesting complement or an alternative to time-consuming procedures aiming at discriminating PPAR ligands with low lipogenic properties.
Patent
3,5-dioxo-(2h,4h)-1,2,4-triazine derivatives as 5ht1a ligands
Jean-Francois Patoiseau,Couret Francoise,Christian Faure,Dupont-Passelaigue Elisabeth,Wouter Koek +4 more
TL;DR: In this paper, the active principle of 3,5-dioxo-(2H,4H)-1,2,4-triazine derivatives of general formula (I) was revealed.
Journal ArticleDOI
Pharmacological profile of F 12511, (S)-2′,3′,5′-trimethyl-4′-hydroxy-α-dodecylthioacetanilide a powerful and systemic acylcoenzyme A: cholesterol acyltransferase inhibitor
Didier Junquero,Philippe Oms,Elisabeth Carilla-Durand,Jean-Marie Autin,Jean-Pierre Tarayre,Anne-Dominique Degryse,Jean-Francois Patoiseau,Francis Colpaert,Andre Delhon +8 more
TL;DR: The results suggest that F 12511, a powerful and systemic ACAT inhibitor, constitutes an appropriate tool to determine whether the inhibition of ACAT constitutes an effective therapy for the treatment of hypercholesterolemia and of atherosclerosis in man.
Patent
3,5-dioxo-(2H,4H)-1,2,4-triazine derivatives
Jean-Francois Patoiseau,Christian Faure,Dupont-Passelaigue Elisabeth,Couret Francoise,Wouter Koek +4 more
TL;DR: In this paper, a novel 3,5-dioxo-(2H,4H-triazine derivatives of general formula (I): wherein R1 is hydrogen, a C1-C4 alkyl radical, phenyl C1 -C4 or phenyl, the phenyl ring being optionally substituted by one or more groupings such as (C 1 -C3) alkyls, hydroxyl, trifluoromethyl or halogen, n can be an integer from 2 to 6; A is a grouping of the ary