J
Jean-Paul Renaud
Researcher at Collège de France
Publications - 2
Citations - 1072
Jean-Paul Renaud is an academic researcher from Collège de France. The author has contributed to research in topics: Retinoic acid receptor & Retinoic acid. The author has an hindex of 2, co-authored 2 publications receiving 1061 citations.
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Journal ArticleDOI
Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid.
Jean-Paul Renaud,Natacha Rochel,Marc Ruff,Valéria Vivat,Pierre Chambon,Hinrich Gronemeyer,Dino Moras +6 more
TL;DR: In this paper, a mouse trap mechanism was proposed to reposition the amphi-pathic α-helix of the AF-2 activating domain and form a transcriptionally active receptor.
Journal ArticleDOI
Purification of the Human RARγ Ligand-Binding Domain and Crystallization of Its Complex with All-transRetinoic Acid
Natacha Rochel,Jean-Paul Renaud,Marc Ruff,Valérie Vivat,Florence Granger,Dominique Bonnier,Thierry Lerouge,Pierre Chambon,Hinrich Gronemeyer,Dino Moras +9 more
TL;DR: A 28kDa fragment of the human retinoic acid receptor γ, hRARγ D 3 E, encompassing the ligand-binding domain (LBD) was overproduced in Escherichia coli and purified as a monomer to more than 95% purity and homogeneity as mentioned in this paper.